系统综述:通过高密度脂蛋白和甘油三酯水平预测新冠肺炎严重程度

Daniel Setiawan Nathan, Hoo Yumilia
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摘要

脂质是SARS-CoV-2感染过程中的一个主要成分。迄今为止,已有几项研究描述了COVID-19期间血浆脂质谱的临床意义。本综述的目的是总结以往关于血浆脂质谱与SARS-CoV-2感染临床严重程度相关性的研究。本版本介绍了与LDL和TG水平相关的研究的迷你综述报告,这些研究可以预测COVID-19患者的严重程度。据报道,感染期间发生的动脉粥样硬化性血脂异常与COVID-19感染中更严重的预后密切相关。因此,应进行脂质分析,以指示COVID-19患者的急性和可测量的炎症,并考虑使用鱼油和他汀类药物治疗来改善病情。
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A Systematic Review: Predict the COVID-19 Severity by HDL and Triglycerides Level
Lipids are a major component in the process of SARS-CoV-2 infection. The clinical significance of plasma lipid profiles during COVID-19 has been described in several studies to date. The purpose of this mini-review is to summarize previous research studies regarding the association of plasma lipid profile with the clinical severity of SARS-CoV-2 infection. This edition presents mini-review reports on research studies related to LDL and TG levels that can predict severity in patients with COVID-19. Atherogenic dyslipidemia that occurs during infection is reported to be very strongly correlated with a more severe prognosis in COVID-19 infection. Therefore, lipid profiles should be performed to indicate acute and measurable inflammation in COVID-19 patients, and fish oil and statin therapy should also be considered to improve the condition.
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