吸烟时间对青年男性肺功能参数的影响

M. ChandrashekharD, Anandkumar, K. JayalakshmiM, P. Babu
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引用次数: 1

摘要

背景:烟草流行是世界有史以来面临的最大公共卫生威胁之一,每年造成800多万人死亡。2002年,全世界约有20%的青少年吸烟,其中一半在青少年时期开始吸烟,预计将持续吸烟15至20年。吸烟会增加患冠状动脉疾病、中风、慢性阻塞性肺病(COPD)和各种恶性肿瘤的风险。吸烟被认为是COPD最重要的致病因素。虽然研究表明吸烟和肺功能的总体“剂量-反应曲线”,但有些人在吸烟几年内就会患上严重疾病,而有些人即使在吸烟多年后也表现出最低程度的临床症状。因此,进行了以下横断面研究,以评估没有明显COPD临床特征的年轻人的肺功能参数随吸烟时间的下降程度。目的:评估吸烟时间对青年成年男性各种肺功能参数的影响。材料和方法:选择50名明显健康的年轻吸烟者进行研究。肺功能测试采用计算机肺活量计(UNI-EM SPIROMIN)进行评估。用ANNOVA分析吸烟时间与各种肺功能参数之间的相关性。结果:所有参数均随吸烟时间的延长而下降,但FVC和FEV1的下降具有统计学意义。结论:吸烟时间与FVC和FEV1值的下降密切相关。
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Impact of Duration of Smoking on Lung Function Parameters in Young Adult Males
Background: The tobacco epidemic is one of the biggest public health threats the world has ever faced,killing more than 8 million people a year. In 2002, about 20% of young teens smoked worldwide, half ofthose who begin smoking in adolescent years are projected to go on to smoke for 15 to 20 years. Smokingincreases the risk of developing coronary artery disease, stroke, chronic obstructive pulmonary disease(COPD) and various malignancies. Smoking is being recognized as the most important causative factor forCOPD. While studies have shown an overall ‘dose response curve” for smoking and lung function, someindividuals develop severe disease within few years of smoking, whereas some individuals show minimalto no clinical symptoms even after many years of smoking. Hence the following cross sectional study wasundertaken to assess the extent of decline in lung function parameters with duration of smoking in youngadults with no apparent clinical features of COPD.Objectives: To assess the impact of duration of smoking on various lung function parameters in young adultmales.Materials and Method: Fifty apparently healthy, young smokers were selected for the study. Pulmonaryfunction test was evaluated by computerized spirometer (UNI-EM SPIROMIN). Correlation betweenduration of smoking and various lung function parameters was analyzed by ANNOVA.Results: All parameters were found to decline with duration of smoking, however the decline in FVC andFEV1 were statistically significant.Conclusion: Duration of smoking is correlated strongly with decline in FVC and FEV1 values.
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