肥胖2型糖尿病患者的味觉功能障碍

A. Hasan, Preethi B L, P. Kalra, A. Kumar M
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摘要

肥胖是许多疾病的一个众所周知的危险因素。众所周知,它会增加许多疾病的并发症,例如2型糖尿病(T2DM)。本研究旨在评估肥胖T2DM患者的味觉功能。本研究旨在评估肥胖T2DM受试者的味觉功能,并将其与瘦T2DM个体进行比较。进行了一项样本量为40的比较研究。将年龄在25至50岁、持续时间<5年且HBA1C≤7的T2DM患者分为2组,I组-体重正常(BMI为18.5至<25),II组为1级肥胖(BMI为30至<35)。三重跌落试验用于评估味觉功能。对不同浓度的品尝剂进行了从“5”到“1”的评分。与瘦型T2DM受试者相比,肥胖糖尿病患者的甜味剂、咸味剂、酸味剂和苦味剂的味觉得分较低。这具有统计学意义(p<0.05)结论:肥胖糖尿病受试者存在味觉障碍。这可能是早期中枢性糖尿病神经病变的指示。味觉减退可能会导致人们对甜味或咸味食物的偏好增加,从而带来更大的健康风险,增加肥胖,并对生活质量产生负面影响。
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Taste dyfunction in obese type 2 diabetic individuals
Obesity is a well-known risk factor for many diseases. It is also known to enhance complications of many diseases eg. Type 2 Diabetes mellitus (T2DM). This study was done to assess the gustatory functions in obese T2DM individuals. This study was done to assess the gustatory functions in obese T2DM subjects and compare the same with lean T2DM individuals. A comparative study with a sample size of 40 was conducted. Patients aged 25 to 50 years with T2DM < 5 years duration and HBA1C ≤ 7 were divided into 2 groups, Group I- with normal weight (BMI of 18.5 to <25) and Group II with grade 1 obesity (BMI of 30 to < 35). Triple Drop Test was done to evaluate gustatory functions. Scoring from “5” to “1” was done on the identification of different concentrations of tastants. Taste scores for sweet, salty, sour, and bitter tastants were lesser in obese diabetics as compared to the lean T2DM subjects. This was statistically significant (p < 0.05) Conclusion: Taste impairment is observed in obese diabetic subjects. This could be an indication of early central diabetic neuropathy. Hypogeusia may cause an increased preference for sweet-tasting or salty foods thus imposing greater health risks, increasing obesity, and negatively affecting the quality of life.
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