播散性肺结核伴多发性骨转移:1例报告

Sp.P Laksmi Wulandari, Putri Mega Juwita
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引用次数: 0

摘要

结核病(TB)是一种由结核分枝杆菌(Mtb)引起的传染性疾病,它攻击各种器官,特别是肺部。结核可与恶性肿瘤同时发生或表现为恶性肿瘤。肺结核可出现多种由其他疾病(包括肿瘤)引起的临床和放射学表现。这些肿瘤被称为伪肿瘤。结核病假性肿瘤是一种罕见的表现,可发生在免疫功能正常的患者在原发性和原发性后结核。结核病假性肿瘤的临床表现无特异性,必须加强临床怀疑,以诊断相关疾病。放射学特征也很难与实际肿瘤区分开来。由于其独特的临床和放射学特征,结核病的典型表现通常易于诊断,但肺癌患者也常出现一些结核病症状。感染患者与恶性肿瘤相似,大多数无症状(> 27%),其余27%表现出与1个月前平均症状不同的症状。临床表现需要大量的误诊导致延误治疗和不必要的程序。对引起恶性肿瘤的结核病例进行诊断是非常重要的,因为感染和恶性过程的管理和结果是完全不同的。因此,我们报告一位24岁的男性肺结核患者,可能是肺癌合并多发性骨转移。侵袭骨骼和关节的肺外结核占所有结核病例的10%至20%。骨和关节结核的位置通常发生在腰椎或胸椎。
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Disseminated Tuberculosis Mimicking Lung Cancer with Multiple Bone Metastasis: A Case Report
Tuberculosis (TB) is a contagious infectious disease caused by Mycobacterium tuberculosis (Mtb) of which attacking various organs particularly the lungs. Tuberculosis can occur together with malignancy or manifest as malignancy. Lung tuberculosis may appear in a variety of clinical and radiological manifestations caused by other diseases including tumors. These tumors are called pseudo-tumors. TB pseudo-tumor is a rare manifestation that can occur in immunocompetent patients in both primary and post-primary TB. The clinical presentation of TB pseudo-tumor is nonspecifi c and the clinical suspicion must be increased to diagnose related diseases. Radiological features can also be challenging to be distinguished from actual tumors. The classic manifestations of pulmonary TB are generally easy to diagnose due to the distinctive clinical and radiological characteristics nonetheless some pulmonary TB symptoms are also often found in patients with lung cancer. Infection patients resemble malignancies most were asymptomatic (> 27%) and the remaining 27% showed symptoms that varied with the average symptoms experienced about 1 month earlier. Clinical presentations that require a lot of misdiagnosis result in delayed treatment and unnecessary procedures. Establishing a diagnosis in cases of tuberculosis that causes malignancy is very important since the management and outcomes of the infection and malignancy process are quite diff erent. Consequently we report a 24-year-old man with tuberculosis possible lung cancer with multiple bone metastase. Extrapulmonary tuberculosis which attacks bones and joints constitutes 10% to 20% of all TB cases. The location of bone and joint TB generally develops in the lumbar or thoracic vertebrae.
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