Psychosis in Wilson's disease: A rare case presentation

Wilson's disease is an uncommon genetic disorder, in which abnormal copper accumulation occurs in various parts of the body. Approximately 30% of patients debut with neuropsychiatric symptoms posing a diagnostic challenge in the initial phase. In this report, we present a case of a middle-aged woman with Wilson's disease who initially developed neurological symptoms such as shaking of hands and jerky movements of the head and later developed psychotic symptoms. We discuss the unique features of our case. Most patients with Wilson's disease develop psychiatric symptoms at some stage. The index case presented with psychosis, which is less commonly described compared to other psychiatric manifestations in patients with Wilson's disease. Currently, there are no treatment guidelines for the management of the same.