纳米壳聚糖研究和创新生物技术应用的知识演变:近期预测和未来预测的多国评估

T. Ekundayo, B. Igere
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引用次数: 0

摘要

由于生物分子制剂在生物技术应用中的多样性,特别是壳聚糖及其衍生物,全球对生物分子制剂的需求日益增长。纳米颗粒技术的进步也促进了基于生物分子的纳米型壳聚糖的使用和功能,产生了纳米基壳聚糖/纳米壳聚糖颗粒。虽然在纳米壳聚糖的探索和创新应用方面取得了显著进展,但未来的扩展仍然模糊不清。本研究从作者、机构、国家、合作网络和生产力等方面对纳米壳聚糖研究和创新生物技术应用的知识演变进行了科学梳理。检索文献5,923篇,作者13,327名,来自Web of Science (WoS)核心馆藏,使用检索标题检索时间跨度为1990 - 2019;(壳聚糖和纳米颗粒*)。我们的结果显示,相关文件的出版以每年第五次的顺序增加。Lotka模型揭示了随后几年观察到的显著增长,年增长率为33.32%;Lotka模型beta=1.927;C = 0.286;R2 = 0.89;p.value = 0.05。通讯作者国家:中国1756(29.65),印度683(11.53),日本47 (0.79);而国家引用是;中国(51720),印度(17595),韩国(10688),澳大利亚(1679)。过去十年的报告揭示了更多关于纳米壳聚糖研究的出版物,从238份出版物到超过746份出版物。尽管纳米壳聚糖的发展揭示了其全球已知的能力、研究基础和/或应用,但仍需要有针对性地开发纳米壳聚糖的潜力、文献、应用、进展和相关研究的未来。这些研究进展在壳聚糖知识研究文献/探索方面的持续应用,对全球未来的研究和生物技术应用具有重要意义。
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KNOWLEDGE EVOLUTION IN NANOCHITOSAN RESEARCH AND INNOVATIVE BIOTECHNOLOGICAL APPLICATIONS: A MULTINATIONAL ASSESSMENT FOR NOWCAST AND FUTURE FORECAST
There had been a growing global need for biomolecular agents due to its diversity in biotechnological application especially chitosan and its derivatives. Current advances in nano-particulate technologies have also abetted the use of biomolecular-based nano-type delivery and functions of chitosan resulting nano-based chitosan/nanochitosan particle. Although there exist notable advances in the exploration and innovative nanochitosan application, future expansion remains bleary. The current study access the knowledge evolution in nanochitosan research and innovative biotechnological applications via science mapping of previous studies from authors, institutions, countries, collaboration networks, and productivity. Retrieved documents were 5,923 with 13,327 authors, from Web of Science (WoS) Core Collection and timespan of 1990 – 2019 using the search title; (Chitosan and nanoparticle*). Our result reveals an increase in the publication of related documents in fifth yearly order. This notable/significant increase observed in subsequent years was revealed by the Lotka’s model with an annual growth rate of 33.32%; Lotka's model beta=1.927; C=0.286; R2=0.89; p.value=0.05. Corresponding Author's Countries were China 1756 (29.65), India 683 (11.53), Japan 47 (0.79); while country citation are; China (51720), India (17595), Korea (10688), Australia (1679). The last decade reports reveal more publications on nanochitosan studies ranging from 238 publications to greater than 746 publications. Although such increase has revealed global known capabilities, research based and/or application of the nanobased-chitosan, there is need for pertinent exploitation of nanochitosan potentials, documentation, application, progresses and future of related studies. A suggestive continuous application of such progresses on chitosan knowledge-research based documentation/exploration has a part with global future research and biotechnological application.
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