幻影上射波刀放射外科系统单、多治疗方案的比较

Kevser Sözen, H. Uysal, Nihal Büyükçi̇zmeci̇, K. Oysul
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引用次数: 0

摘要

随着射波刀放射外科系统的使用越来越多,治疗方案的选择也很重要。在本研究中,通过比较所有转移灶一次性照射和转移灶单独照射方案在多发脑转移中的应用,以确定更有利的应用。为此,在一个全新的头幻影;6个脑转移灶和3个关键器官,包括脊髓、脑干和交叉,在放置剂量计的间隙上进行了测定。取头部幻象的CT图像,在图像上画出这6个肿瘤和3个关键器官(轮廓)。在治疗计划系统中,我们要给的剂量是书面的辐照计划是单独制定的一次辐照。每次照射后,将BeO光激发的发光(OSL)剂量计从体模中取出,并记录从剂量计读取器获得的计数值。比较一次性和单独照射的均匀性指数(HI)、一致性指数(CI)、新一致性指数(nCI)、治疗时间和梯度指数(GI)值。虽然在符合性指数(CI)、新符合性指数(nCI)、均匀性指数(HI)和覆盖值方面发现单独治疗方案照射肿瘤更有优势,但在梯度指数和持续时间方面发现单一方案更适合。
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Comparison of Single and Multiple Treatment Plans Made in CyberKnife® Radiosurgery System on Phantom
While the use of CyberKnife® radiosurgery systems is increasing, the choice of treatment plan is also important. In this study, it was aimed to determine the more advantageous application by comparing the irradiation of all metastases at once and the protocols of irradiation of metastases separately in multiple brain metastases. For this, on an entirely new head phantom; 6 brain metastases and 3 critical organs, including the spinal cord, brain stem, and chiasm, were determined over the spaces where the dosimeters were placed. Computed tomography (CT) images of the head phantom were taken and these 6 tumors and 3 critical organs were drawn (contouring) on the image. In the treatment planning system, the dose we wanted to give was written and irradiation plans were created to be done separately with a single irradiation. Luminescence (OSL) dosimeters with BeO optical excitation were removed from the phantom after each irradiation and the count value obtained from the dosimeter reader device was recorded. Homogeneity index (HI), conformity index (CI), new conformity index (nCI), duration of treatment, and gradient index (GI) values of irradiation at one time and separately were compared. While it was found that irradiation of tumors with a separate treatment plan was more advantageous in terms of conformity index (CI), new conformity index (nCI), homogeneity index (HI), and coverage values, it was seen that a single plan was more suitable in terms of gradient index and duration.
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