利用微生物生物合成金属纳米粒子及其医学应用

Q3 Agricultural and Biological Sciences Novel Research in Microbiology Journal Pub Date : 2021-02-01 DOI:10.21608/NRMJ.2021.149378
Maysaa T. Alloosh, Walid Khaddam, Adbulsalam K. Almuhammady
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引用次数: 5

摘要

纳米技术是进入多个领域的最重要的技术之一,因为它依赖于纳米级粒子的合成,称为纳米颗粒(NPs)。纳米颗粒的生物合成可以利用植物或微生物来完成;然而,利用微生物合成NPs是一种经济且环保的方法。本文综述了利用多种微生物如;用于生物合成一些金属纳米粒子的细菌、放线菌、真菌和藻类包括;银、金、钯、硒、镁、二氧化钛、氧化锌……等,在简单的制造条件下,在短时间内,从几分钟到几天。所得NPs对几种主要引起人类重要疾病的真菌具有抗真菌潜力;白色念珠菌和黑曲霉。此外,NPs对金黄色葡萄球菌和铜绿假单胞菌具有抗菌作用,近年来对青霉素、甲氧西林等几种抗生素的影响减弱。本文的综述将对NPs生物合成和纳米医学应用领域的研究人员有所帮助。
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Biosynthesis of metal nanoparticles using microorganisms and its medicinal applications
Nanotechnology is one of the most important technologies that enter into multiple fields, as it depends on the synthesis of particles with nano scale called nanoparticles (NPs).  Biosynthesis of nanoparticles can be done using plants or microorganisms; however, synthesis of NPs using microorganisms is economical and an ecofriendly method. This review article provides highlights on the latest studies on using diverse microorganisms such as; bacteria, actinobacteria, fungi and algae for the biosynthesis of some metal nanoparticles including; silver, gold, palladium, selenium, magnesium, titanium dioxide, zinc oxide.. etc,  under simple manufacturing conditions and within a short period that ranges from a few minutes to several days. The resulting NPs mostly show anti-fungal potential towards several fungal species that cause important human diseases mainly; Candida albicans and Aspergillus niger.  Moreover, NPs has antibacterial efficacy against Staphylococcus aureus and Pseudomonas aeruginosa, which recently become less affected by several antibiotics like penicillin and methicillin. This review will help the researchers who work in biosynthesis of NPs and in the nano-medical application fields.
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来源期刊
CiteScore
1.40
自引率
0.00%
发文量
16
审稿时长
4 weeks
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