监狱系统中艾滋病毒感染流行过程的发展

S. E. Kondratova, A. Marchenko
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引用次数: 0

摘要

目的陈述旨在识别和评估高危人群高集中地区艾滋病毒感染流行过程发展所确定的风险因素。研究对象。确定了365名艾滋病毒感染者,其中:研究组——根据秋明市联邦监狱服务局地区医院,2008-2018年期间222名囚犯感染艾滋病毒死亡;对照组——2011-2018年期间,143名死于HIV的平民(守法)患者根据地区传染病医院感染。研究方法。本研究采用流行病学研究、数学建模和预测、逐步纳入的逻辑回归和ROC分析等方法。后果为了评估与拘留场所艾滋病毒感染率有关的流行病学状况,研究了流行病发展过程的长期动态,并评估了优先风险因素,预测艾滋病病毒感染流行过程的发展,建立长期对平民人口的社会意义和风险。HIV阳性男性服刑期间出现致命后果的概率是平民男性的4.7倍,而通过胃肠外(麻醉)感染感染HIV时高14.6倍,伴有病毒性肝炎时高4.8倍,有呼吸道疾病时高20倍,在HIV感染的临床阶段高99.2%3,4A,4B。结论囚犯感染艾滋病毒的情况不利,死亡率高。现阶段应加强一套防止艾滋病毒在囚犯中传播的组织和预防措施,重点关注感染风险和进展增加的群体。
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Development of the epidemic process of HIV infection in the penitentiary system
The purpose statement is to identify and assess the risk factors determined by the development of the epidemic process of HIV infection in the area of high concentration of the risk group.Object of study. 365 deceased HIV-infected were identified, of which: the study group — 222 prisoners who died HIV-infected on the basis of the Regional Hospital of the Federal Penitentiary Service of the city of Tyumen for the period 2008–2018; control group — 143 civilian (law-abiding) patients who died HIVinfected on the basis of the Regional Infectious Diseases Hospital for the period 2011–2018.Research methods. The work used the methods of epidemiological research, mathematical modeling and forecasting, logistic regression of stepwise inclusion with ROC analysis.Results. To assess the epidemiological situation in relation to the incidence of HIV infection in places of detention, the longterm dynamics of the development of the epidemic process was studied with an assessment of priority risk factors, forecasting the development of the epidemic process of HIV infection with the establishment of social significance and risk for the civilian population over a long period. The probability of developing a fatal outcome in HIV-positive men serving sentences is 4.7 times higher than among civilian men, while 14.6 times higher when infected with HIV by parenteral (narcotic) infection, 4.8 times higher with concomitant viral hepatitis and 20 times higher in the presence of a respiratory disease, 99.2% higher in the clinical stages of HIV infection 3, 4A, 4B than in civilians.Conclusion. Prisoners have an unfavorable situation for HIV infection with high mortality. A set of organizational and preventive measures to prevent the spread of HIV among prisoners at the present stage should be strengthened with an emphasis on groups at increased risk and progression of infection. 
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来源期刊
HIV Infection and Immunosuppressive Disorders
HIV Infection and Immunosuppressive Disorders Medicine-Infectious Diseases
CiteScore
0.70
自引率
0.00%
发文量
37
期刊介绍: In the scientific-practical journal "HIV Infection and Immunosuppressive Disorders", published various issues of HIV medicine (epidemiology, molecular mechanisms of pathogenesis to the development of educational programs) leading scientists of Russia and countries of CIS, USA, as well as practical healthcare professionals working in research centers, research institutes, universities, clinics where done basic medical work. A special place on the pages of the publication is given to basic and clinical research, analytical reviews of contemporary and foreign reports, the provision of medical care for various diseases.
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