血小板-淋巴细胞比率作为口腔癌症患者的预后指标

IF 0.7 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Journal of Maxillofacial & Oral Surgery Pub Date : 2025-02-01 Epub Date: 2023-07-12 DOI:10.1007/s12663-023-01959-8
Bahiya Elrashid Khalid Hamad, Yousif I Eltohami, Ahmed Mohamed Suleiman
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引用次数: 0

摘要

目的:探讨血小板淋巴细胞比例作为苏丹OSCC患者预后的临床参数的预测价值。方法:选取42例口腔癌患者进行研究。这些患者在2018年12月至2020年6月期间接受了手术治疗。记录PLR,并与手术切缘状态、淋巴血管侵袭、结外延伸、显微深度和患者生存(死/活)相关。结果:以170为PLR的分界点;比值大于170的患者预后较差。24例(59.5%)患者PLR高于170。PLR等于或小于170的患者生存几率降低45%,淋巴结阳性几率降低57%。33%的人去世了。结论:PLR是一种经济、实用、有效的预测OSCC患者总生存期的方法。
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Platelet Lymphocyte Ratio as a Prognosticator in Oral Cancer Patients.

Objective: To study the prognostic predictive value of the platelet lymphocyte ratio as a clinical parameter of the outcome of the Sudanese OSCC patients.

Method: Forty two oral cancer patients were selected for the study. The patients surgically managed in the period December 2018 to June 2020. The PLR was recorded and correlated with :the status of surgical margins, the lymphovascular invasion, the extranodal extension, the microscopic depth and the patient's survival (dead/ alive).

Result: A ratio of 170 was considered to be a cut off point of the PLR; as patients with a ratio higher than 170 were found to have a bad prognosis. Twenty-four patients (59.5%) had a PLR higher than 170. Patients with PLR equal to 170 or less have 45% decrease in the odds of survival and 57% decrease in the odds of having positive lymph nodes. Thirty-three percent passed away.

Conclusion: The PLR is an affordable, practical and efficient way to predict an OSCC patient's overall survival.

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来源期刊
Journal of Maxillofacial & Oral Surgery
Journal of Maxillofacial & Oral Surgery DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
1.90
自引率
0.00%
发文量
138
期刊介绍: This journal offers comprehensive coverage of new techniques, important developments and innovative ideas in Oral and Maxillofacial Surgery. Practice-applicable articles help develop the methods used to handle dentoalveolar surgery, facial injuries and deformities, TMJ disorders, oral cancer, jaw reconstruction, anesthesia and analgesia. The journal also includes specifics on new instruments, diagnostic equipment’s and modern therapeutic drugs and devices. Journal of Oral and Maxillofacial Surgery is recommended for first or priority subscription by the Dental Section of the Medical Library Association. Specific topics covered recently have included: ? distraction osteogenesis ? synthetic bone substitutes ? fibroblast growth factors ? fetal wound healing ? skull base surgery ? computer-assisted surgery ? vascularized bone grafts Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services.
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