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An Unusual Case of Dacryocystitis After Dacryocystectomy: Is It Still Possible to Perform a Dacryocystorhinostomy? 一个罕见的泪囊炎病例后泪囊切除术:是否仍然可以进行泪囊鼻腔造口术?
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2023-07-20 DOI: 10.1007/s12663-023-01940-5
Paola Bonavolontà, Simona Barone, Giovanna Norino, Vincenzo Abbate, Antonio Romano, Giorgio Iaconetta, Riccardo Villari, Luigi Califano

This is a rare case of a patient who developed a relapse of dacryocystitis and maxillary sinusitis although previous dacryocystectomy. We decided to perform an external dacryocystorhinostomy to remove the scar and the residual part of the lacrimal sac combined with endoscopic sinus surgery (ESS) to solve the symptoms.

这是一个罕见的病例,患者曾接受过泪囊切除术,但泪囊炎和上颌窦炎又复发了。我们决定进行外侧泪囊鼻腔造口术,切除疤痕和泪囊残留部分,并结合内窥镜鼻窦手术(ESS)来解决症状。
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引用次数: 0
IS Intra-masseteric Dexamethasone Better than Intra-deltoid Injection in Reducing Post-operative Sequelae Following Impacted Third Molar Surgery?: A Randomized Clinical Study. 在减少影响性第三磨牙手术的术后后遗症方面,弥散注射地塞米松比三角肌内注射地塞米松效果更好吗?随机临床研究。
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-08-13 DOI: 10.1007/s12663-024-02308-z
Arpit Gupta, Sujata Mohanty, Pankaj Sharma, Zainab Chaudhary, Anjali Verma, S Hemavathy

Aim: The post-operative sequelae of third molar surgical extractions need to be controlled in order to reduce patient morbidity. Dexamethasone is a well-researched drug which has established its merit as an anti-inflammatory agent. The aim of this randomized clinical study was to compare the patient-centric outcomes after pre-emptive intramuscular injection of dexamethasone into the masseter and deltoid, respectively.

Materials and methods: The outcomes measured were pain, facial swelling and mouth-opening postoperatively on Day 1, 3 and 7. The subjects were randomly divided into two groups. Group 1 received an intra-oral injection of 8 mg of dexamethasone into the masseter muscle and a placebo injection of distilled-water into the deltoid muscle 2 h before surgical removal of impacted mandibular third molar. Group 2 received an intra-oral placebo injection of distilled-water into masseter muscle and an 8 mg injection of dexamethasone into deltoid muscle.

Results: On comparison, Group 1 patients experienced statistically significant less pain (VAS score on day 1, 3, and 7), facial swelling (day 1, 3), and restricted mouth-opening (day 1, 3).

Conclusion: The study concluded that pre-emptive dexamethasone injection, at masseter or deltoid, is helpful in reducing post-operative sequelae of mandibular third molar extraction. However, the immediate post-operative outcomes were found to be better mitigated when the injection was administered locally into masseter muscle.

目的:需要控制第三磨牙手术拔除的术后后遗症,以降低患者的发病率。地塞米松是一种经过充分研究的药物,其作为抗炎药物的优点已得到证实。这项随机临床研究的目的是比较在肌肉注射地塞米松后,以患者为中心的治疗效果:测量结果为术后第 1、3 和 7 天的疼痛、面部肿胀和张口情况。受试者被随机分为两组。第一组在手术切除下颌第三磨牙前 2 小时,在咀嚼肌内注射 8 毫克地塞米松,在三角肌内注射蒸馏水作为安慰剂。第 2 组患者在口腔内向颌间肌注射蒸馏水安慰剂,并向三角肌注射 8 毫克地塞米松:结果:相比之下,第 1 组患者的疼痛(第 1、3 和 7 天的 VAS 评分)、面部肿胀(第 1、3 天)和张口受限(第 1、3 天)明显减少:该研究得出结论,在下颌第三磨牙拔除术前,在肌肉群或三角肌注射地塞米松有助于减少术后后遗症。不过,如果在局部肌肉注射地塞米松,则能更好地减轻术后即刻出现的后遗症。
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引用次数: 0
Recurrence and Prognosticators of Recurrence in Odontogenic Keratocyst of the Jaws. 颌骨牙源性角化囊肿复发及预后因素分析
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2023-01-05 DOI: 10.1007/s12663-022-01846-8
Rathindra Nath Bera, Sapna Tandon, Preeti Tiwari, Madan Mishra

Introduction: The incidence of recurrence of OKC varied from 2.5 to 62%. Studies have linked recurrence to treatment methods and also clinical and pathological features. The aim of this study was to evaluate the 5-year recurrence and the factors associated with recurrence in odontogenic keratocysts of the jaws.

Methods: A retrospective review of records was done from the Institute's Medical Records Directory from 2010 to 2021. The following data were obtained of the lesion; age at presentation, gender, site, subsite, radiographic presentation (locularity), radiographic borders, presence or absence of satellite cysts, inflammatory infiltrate, and treatment rendered presence or absence of cortical perforation and soft-tissue extension and presence or absence of recurrence. Kaplan Meir estimator was used to evaluate recurrence rate and log rank test was used to compare the survival amongst groups. Cox regression analysis was used to evaluate the odds ratio to find out the possible factors influencing risk of recurrence. A p value of < 0.05 was considered statistically significant at 95% confidence interval.

Results: In our study cohort, 27.2% of patients had recurrence. Posterior maxillary lesions, multilocular lesions, lesions with scalloped borders, presence of soft-tissue extension and cortical perforation, presence of satellite cysts and inflammatory infiltrate and enucleation with peripheral ostectomy were significantly associated with recurrence. However, soft-tissue extension, cortical perforation, multilocular lesions and presence of satellite cysts were independent risk factors.

Conclusion: There is still debate on the best treatment modality for the management of OKCs. More studies are required to quantify the results.

介绍:OKC 的复发率从 2.5% 到 62% 不等。研究表明,复发与治疗方法以及临床和病理特征有关。本研究旨在评估颌骨牙源性角化囊肿的 5 年复发率以及与复发相关的因素:方法:对研究所病历目录中 2010 年至 2021 年的病历进行回顾性审查。获得了病变的以下数据:发病年龄、性别、部位、亚部位、影像学表现(定位)、影像学边界、有无卫星囊肿、炎症浸润、治疗效果、有无皮质穿孔和软组织扩展以及有无复发。采用 Kaplan Meir 估计器评估复发率,采用对数秩检验比较各组间的存活率。采用 Cox 回归分析评估几率比,以找出影响复发风险的可能因素。结果在我们的研究队列中,27.2%的患者复发。上颌后部病变、多房病变、病变边界呈扇形、存在软组织扩展和皮质穿孔、存在卫星囊肿和炎性浸润以及进行周边切除术的去核手术与复发显著相关。然而,软组织扩展、皮质穿孔、多房病变和卫星囊肿的存在是独立的风险因素:结论:关于治疗 OKCs 的最佳治疗方式仍存在争议。结论:关于治疗 OKCs 的最佳治疗方式仍存在争议,需要更多的研究来量化结果。
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引用次数: 0
Impact of Prehabilitation With Preoperative Swallowing Exercises on Postoperative Swallowing Morbidity in Oral Cavity Cancer: Randomized Controlled Trial. 术前吞咽训练对口腔癌术后吞咽发病率的影响:随机对照试验
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-09-03 DOI: 10.1007/s12663-024-02324-z
Subbiah Shanmugam, R R Pravenkumar

Background and objective: Oral cancer surgery and the associated reconstructive procedures cause mechanical and neurological impairment of swallowing. Despite postoperative rehabilitation, functional impairment of swallowing remains a concern. This study is to investigate the potential benefits of prehabilitation with preoperative swallowing exercises to patients undergoing composite resections and compartmental tongue resections so that it results in better swallowing outcomes and improved quality of life after surgery.

Materials and methods: Sixty patients included in the study were randomized into an exercise and control group of 30 each. Patients with squamous cell carcinoma of the oral cavity undergoing composite resection or compartmental tongue resections were included, and patients with severe trismus at presentation were excluded. Patients in the exercise group were instructed on a set of six active exercises to be followed strictly for a period of at least 1 week before surgery. Preoperative swallowing exercises comprised of evidence-based exercises targeting the muscle groups involved in swallowing. Postoperative swallowing rehabilitation was the same as that of the control group. Patients were assessed after 6 months of surgery. Outcomes were assessed both subjectively and objectively. Objective assessment was done by inexpensive, novel clinical methods of repetitive saliva swallow test (RSST), water swallow test (WST) and food swallow test (FST) to and graded using dysphagia severity scale (1-7).

Results: Average oral intake scale (1-Oral solids, 2-Oral semisolids/easy to chew foods, 3-Oral liquids only and 4-Non-oral, orogastric tube dependent) assessed subjectively was significantly lower in exercise arm, and the control arm had a significantly higher OIS score. Exercise arm had higher number of patients in DSS scores of 5, 6 and 7. The control arm had a higher number of patients in DSS scores of 3 and 4. The differences between the two groups were found to be statistically significant taking into consideration the confounding factors of radiation, wound morbidity and tongue resections.

Conclusion: Preoperative swallowing exercises have shown a positive impact on postoperative swallowing ability. This is the first randomized trial to assess the effect of PSE in postoperative oral cancer patients. Our exercise protocol needs standardization, and clinical objective method of dysphagia assessment requires further validation. However, prehabilitation with PSE has the potential to improve the quality of life in oral cancer patients.

背景和目的:口腔癌手术和相关的整形手术会造成吞咽功能的机械和神经损伤。尽管进行了术后康复,但吞咽功能障碍仍是一个令人担忧的问题。本研究旨在探讨通过术前吞咽运动进行术前康复训练对接受复合切除术和舌分隔切除术患者的潜在益处,从而改善吞咽效果,提高术后生活质量:研究中的 60 名患者被随机分为运动组和对照组,每组 30 人。研究对象包括接受复合切除术或舌分隔切除术的口腔鳞状细胞癌患者,不包括出现严重三趾骨畸形的患者。运动组患者在术前至少一周内严格遵守一套六项主动运动的指导。术前吞咽运动包括以证据为基础的针对吞咽肌肉群的运动。术后吞咽康复训练与对照组相同。手术 6 个月后对患者进行评估。对结果进行了主观和客观评估。客观评估采用重复唾液吞咽试验(RSST)、水吞咽试验(WST)和食物吞咽试验(FST)等廉价、新颖的临床方法,并使用吞咽困难严重程度量表(1-7)进行分级:根据主观评估得出的平均口腔摄入量表(1-口腔固体、2-口腔半固体/易咀嚼食物、3-仅口腔液体和 4-非口腔、依赖口胃管的食物)在运动组明显较低,而对照组的 OIS 分数明显较高。运动组中 DSS 评分为 5、6 和 7 分的患者人数较多。对照组中 DSS 评分为 3 分和 4 分的患者人数较多。考虑到辐射、伤口发病率和舌头切除术等混杂因素,两组之间的差异具有统计学意义:结论:术前吞咽练习对术后吞咽能力有积极影响。这是首个评估 PSE 对口腔癌术后患者影响的随机试验。我们的训练方案需要标准化,吞咽困难的临床客观评估方法也需要进一步验证。不过,使用 PSE 进行术前康复训练有可能改善口腔癌患者的生活质量。
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引用次数: 0
Shame and Stigma Over Long-Term Survival in Postoperative Cases of Head and Neck Cancer. 头颈癌术后患者的羞耻感和耻辱感对长期生存的影响
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2023-05-14 DOI: 10.1007/s12663-023-01931-6
Atul Kumar Goyal, Jaimanti Bakshi, Naresh K Panda, Rakesh Kapoor, Dharam Vir, Krishan Kumar, Pankaj Aneja

Background: Surgical excision of the tumor remains the primary choice for the treatment of head and neck cancer patients, but it often leads to facial disfigurement, which further causes mutilation in the patients. Mutilation causes shame and stigma, which imparts significant psychological strain on patients, and tends to impair their quality of life.

Objective: The present study aimed to assess the shame and stigma over long-term postoperative survival duration in head and neck cancer patients.

Methodology: Total 100 postoperative patients of head and neck cancer were recruited from the outpatient department of the host institute, and shame and stigma was assessed using the Hindi version of the shame and stigma scale.

Results: The global shame and stigma score was 22.67 ± 16.22, with the highest perceived stigma due to changes in appearance (11.94 ± 8.805), followed by impaired speech (4.490 ± 3.243), feeling of regret (3.950 ± 3.313), and feeling of stigma (4.490 ± 3.243). The shame and stigma was found to be significantly higher in maxillary cancer patients (33.22 ± 16.60), followed by larynx cancer patients (22.06 ± 13.41) and oral cancer patients (21.53 ± 16.49). Patients with stage III and stage IV of cancer were found to perceive higher shame and stigma (35.91 ± 22.23 and 27.36 ± 14.71, respectively) compared to the patients having stage I and stage II cancer (9.583 ± 9.709 and 16.44 ± 11.82, respectively). A significantly declining linear trend was found between shame and stigma and postoperative survival duration.

Conclusion: We concluded that shame and stigma act as important determinants of quality of life over long-term survival in head and neck cancer patients, and should be considered while designing psychological interventions and surgical reconstruction protocols. The present study will help clinicians to assess the mutilation among head and neck cancer patients in a better way and will help in devising new psychological strategies to manage psychological aspects associated with mutilation, which will ultimately enhance the quality of life of patients.

背景:手术切除肿瘤仍是治疗头颈部癌症患者的主要选择,但往往会导致面部毁容,进一步造成患者残缺。毁容会给患者带来羞耻感和耻辱感,给患者造成巨大的心理压力,往往会影响他们的生活质量:本研究旨在评估头颈部癌症患者术后长期存活期间的羞耻感和耻辱感:从主办研究所的门诊部共招募 100 名头颈部癌症术后患者,使用印地语版羞耻感和耻辱感量表对其羞耻感和耻辱感进行评估:总体羞耻感和耻辱感得分为(22.67 ± 16.22)分,其中因外貌改变而产生的耻辱感最高(11.94 ± 8.805),其次是言语障碍(4.490 ± 3.243)、遗憾感(3.950 ± 3.313)和耻辱感(4.490 ± 3.243)。上颌骨癌患者的羞耻感和耻辱感明显较高(33.22 ± 16.60),其次是喉癌患者(22.06 ± 13.41)和口腔癌患者(21.53 ± 16.49)。与 I 期和 II 期癌症患者(分别为 9.583 ± 9.709 和 16.44 ± 11.82)相比,III 期和 IV 期癌症患者的羞耻感和耻辱感更高(分别为 35.91 ± 22.23 和 27.36 ± 14.71)。羞耻感和耻辱感与术后生存期之间呈明显的线性下降趋势:我们得出结论:羞耻感和耻辱感是影响头颈部癌症患者长期生存的生活质量的重要决定因素,在设计心理干预和手术重建方案时应加以考虑。本研究将有助于临床医生更好地评估头颈部癌症患者的残割情况,并有助于制定新的心理策略来管理与残割相关的心理问题,最终提高患者的生活质量。
{"title":"Shame and Stigma Over Long-Term Survival in Postoperative Cases of Head and Neck Cancer.","authors":"Atul Kumar Goyal, Jaimanti Bakshi, Naresh K Panda, Rakesh Kapoor, Dharam Vir, Krishan Kumar, Pankaj Aneja","doi":"10.1007/s12663-023-01931-6","DOIUrl":"10.1007/s12663-023-01931-6","url":null,"abstract":"<p><strong>Background: </strong>Surgical excision of the tumor remains the primary choice for the treatment of head and neck cancer patients, but it often leads to facial disfigurement, which further causes mutilation in the patients. Mutilation causes shame and stigma, which imparts significant psychological strain on patients, and tends to impair their quality of life.</p><p><strong>Objective: </strong>The present study aimed to assess the shame and stigma over long-term postoperative survival duration in head and neck cancer patients.</p><p><strong>Methodology: </strong>Total 100 postoperative patients of head and neck cancer were recruited from the outpatient department of the host institute, and shame and stigma was assessed using the Hindi version of the shame and stigma scale.</p><p><strong>Results: </strong>The global shame and stigma score was 22.67 ± 16.22, with the highest perceived stigma due to changes in appearance (11.94 ± 8.805), followed by impaired speech (4.490 ± 3.243), feeling of regret (3.950 ± 3.313), and feeling of stigma (4.490 ± 3.243). The shame and stigma was found to be significantly higher in maxillary cancer patients (33.22 ± 16.60), followed by larynx cancer patients (22.06 ± 13.41) and oral cancer patients (21.53 ± 16.49). Patients with stage III and stage IV of cancer were found to perceive higher shame and stigma (35.91 ± 22.23 and 27.36 ± 14.71, respectively) compared to the patients having stage I and stage II cancer (9.583 ± 9.709 and 16.44 ± 11.82, respectively). A significantly declining linear trend was found between shame and stigma and postoperative survival duration.</p><p><strong>Conclusion: </strong>We concluded that shame and stigma act as important determinants of quality of life over long-term survival in head and neck cancer patients, and should be considered while designing psychological interventions and surgical reconstruction protocols. The present study will help clinicians to assess the mutilation among head and neck cancer patients in a better way and will help in devising new psychological strategies to manage psychological aspects associated with mutilation, which will ultimately enhance the quality of life of patients.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"1 1","pages":"1057-1062"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11456006/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42322560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comparative Study of Efficacy for Extra-Oral vs. Intra-Oral Mandibular Nerve Block in Arch Bar Fixation for Management of Mandibular Fractures. 下颌骨骨折弓形固定术中口腔外下颌神经阻滞与口腔内下颌神经阻滞疗效比较研究。
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-08-17 DOI: 10.1007/s12663-024-02306-1
Monika Gupta, Aaquib Nazir, Atul Sharma, Amit Bali

Purpose: The aim of the study was to evaluate and compare the efficacy of extra-oral mandibular nerve block (infra-zygomatic approach/lateral approach) vs. intra-oral (Gow-Gates) mandibular nerve block in arch bar fixation for management of mandibular fractures.

Methodology: A total of 200 patients reported with maxillofacial fractures. Out of them, 50 patients who required arch bar fixation for management of mandibular fractures were divided into two groups: Group I: Extra-oral and Group II: Intra-oral mandibular nerve blocks. The intra-operative pain, time of onset of anaesthesia, volume of drug administered, depth of needle insertion, repetition of injections and postoperative complications were analysed.

Results: In Group I (Extra-oral nerve block), the time of onset of anaesthesia, volume of anaesthesia administered, needle depth, number of repetition of injections and postoperative complications were more as compared to Group II. No significant difference was observed in intra-operative pain score between two groups.

Conclusion: Intra-oral approach with Gow-Gates technique seemed to be efficient and easy to operate as compared to extra-oral approach, for arch bar fixation of mandibular fractures in an output door setting, as extra-oral approach is more technique-sensitive and may lead to certain complications which require operation theatre setting with medical attention.

目的:该研究旨在评估和比较下颌神经口外阻滞(颧下入路/外侧入路)与下颌神经口内阻滞(Gow-Gates)在下颌骨骨折弓形固定术中的疗效:共有 200 名颌面部骨折患者。其中,50 名下颌骨骨折患者需要接受弓形固定治疗,他们被分为两组:第一组:口外下颌神经阻滞;第二组:口内下颌神经阻滞。对术中疼痛、麻醉开始时间、给药量、针插入深度、重复注射和术后并发症进行了分析:结果:与第二组相比,第一组(口外神经阻滞)的麻醉开始时间、用药量、针刺深度、重复注射次数和术后并发症更多。两组术中疼痛评分无明显差异:结论:与口外方法相比,采用高-盖茨技术的口内方法在输出门环境下进行下颌骨骨折的弓形固定似乎更有效、更易于操作,因为口外方法对技术更敏感,可能会导致某些并发症,需要在手术室环境下进行治疗。
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引用次数: 0
Validation of Low Cost Patient Specific Implant Design Using Finite Element Analysis (FEA) for Reconstruction of Segmental Mandibular Defects: A Case Report and Literature Review. 利用有限元分析(FEA)验证低成本患者特异性种植体设计用于重建下颌骨节段性缺损:1例报告和文献回顾
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2023-04-30 DOI: 10.1007/s12663-023-01926-3
Chitra Chakravarthy, Ravi S Patil, Shivraj Wagdargi, Santosh Kumar Malyala, Daisy Arahna Sofhia, Chethan V Babu, Rakesh Koppunur, Aishwarya Mundodi

Introduction: Mandibular continuity defects can cause functional and cosmetic deformities affecting a patient's quality of life. Reconstruction of such defects can be intricate even for the most seasoned maxillofacial surgeons. Reconstruction plates were the standard of care in the past, followed by a secondary reconstruction using autogenous grafts.

Materials and methods: Novel technological upgrades like customized computer-designed patient-specific implants (PSIs) have overtaken these stock reconstruction plates to enhance the aesthetics and address the individual clinical situation. Affirmation of the above plate design using biomechanical analysis can further improve the efficacy of PSIs.

Discussion: The present case report describes a novel combination of an autogenous graft and a low-cost patient-specific implant with the prosthesis design validated using finite element analysis. The authors have also reviewed the biomechanical evaluation of PSIs design and its uses in treating mandibular continuity defects.

Conclusion: Use of FEA helped to inspect the potential weakness and stress distribution through out the implant due to this there was no sign of hardware failure.

简介下颌连续性缺损会导致功能和外观畸形,影响患者的生活质量。即使对经验最丰富的颌面外科医生来说,此类缺损的重建也是错综复杂的。重建板是过去的标准护理方法,然后使用自体移植物进行二次重建:新技术的升级,如计算机定制的患者特异性植入体(PSI),已经取代了这些重建板,以提高美观度并解决个别临床情况。通过生物力学分析确认上述植入板的设计可以进一步提高 PSIs 的功效:本病例报告描述了自体移植物和低成本患者专用植入物的新型组合,并通过有限元分析对假体设计进行了验证。作者还回顾了 PSIs 设计的生物力学评估及其在治疗下颌连续性缺损中的应用:有限元分析有助于检查种植体的潜在弱点和应力分布,因此没有出现硬件故障的迹象。
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引用次数: 0
A Novel Method of Fixation and Stabilization of the Nasoendotracheal Tube for Maxillary Osteotomies: The Head Cap Technique. 上颌骨截骨术中固定和稳定鼻内气管导管的新方法:头帽技术
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-08-23 DOI: 10.1007/s12663-024-02316-z
David P Tauro, Uday Kiran Uppada

Purpose: To propose a novel technique of fixation and stabilization of the nasoendotracheal tube for maxillary osteotomies.

Method: The technique utilizes a flexible Portex north pole endotracheal tube size 6, elastic adhesive tape, a catheter mount and a head cap made of cloth in the fixation and stabilization of the nasoendotracheal tube for maxillary osteotomies.

Result: It is a simple method of fixation and stabilization of the nasoendotracheal tube, particularly for maxillary osteotomies that essentially eliminates distortion of the nasal, labial and perinasal areas and facilitates good nasolabial control during maxillary osteotomies.

Conclusion: This technique is simple, safe and versatile and may be employed for maxillary osteotomies.

目的:提出一种固定和稳定上颌骨截骨术鼻内气管导管的新技术:方法:该技术利用柔韧的 6 号 Portex 北极气管导管、弹性胶带、导管支架和布制头帽来固定和稳定上颌骨截骨术的鼻内气管导管:结果:这是一种固定和稳定鼻内气管导管的简单方法,尤其适用于上颌骨截骨术,可从根本上消除鼻腔、唇部和鼻周区域的变形,并有助于在上颌骨截骨术中实现良好的鼻唇控制:该技术简单、安全且用途广泛,可用于上颌骨截骨术。
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引用次数: 0
Exotic Keratin Pearl Degradation Mechanism by Giant Cells in Oral Squamous Cell Carcinoma and its Plausible Hypothesis. 口腔鳞状细胞癌中巨细胞的外来角蛋白珠降解机制及其似是而非的假设
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2024-08-31 DOI: 10.1007/s12663-024-02319-w
R Keerthika, Akhilesh Chandra, Rahul Agrawal

Introduction: Oral squamous cell carcinoma (OSCC) is a formidable malignancy in the Indian subcontinent, characterized by high morbidity and mortality, with a dismal 5-year survival rate of 40-50%. The tumor's histopathological heterogeneity is well documented, particularly in its differentiation status, which ranges from well-differentiated lesions with prominent keratin pearls to poorly differentiated forms lacking such structures.

Objectives: Existing literature has elucidated the role of neutrophils and macrophages in the degradation of keratin pearls, the involvement of multinucleated giant cells (MNGCs) in this process remains cryptic.

Case report: This study reports a novel case of a 49-year-old male with moderately differentiated OSCC, characterized by ulcerative growth in the left buccal mucosa. Histopathological analysis revealed neoplastic cell infiltration, keratinization, and abnormal mitoses, alongside the degradation of keratin pearls by large foreign body and Langhans MNGCs. This intricate keratin pearl degradation by MNGCs in OSCC highlights tumor heterogeneity and aggressiveness, offering profound insights into surgical, radiotherapy, and chemotherapy strategies. Surgeons must meticulously consider this process as a marker of aggressive behavior, warranting precise surgical planning and a multidisciplinary approach for optimal outcomes.

Conclusion: This case emphasizes the critical role of foreign body and Langhans MNGCs in the degradation of keratin pearls within OSCC, revealing a hitherto unrecognized facet of tumor biology. This discovery holds profound implications for understanding OSCC progression, prognosis, and therapeutic responsiveness, warranting further investigation into the molecular mechanisms underpinning this process.

简介在印度次大陆,口腔鳞状细胞癌(OSCC)是一种可怕的恶性肿瘤,发病率和死亡率都很高,5年生存率仅为40%至50%。该肿瘤的组织病理学异质性已得到充分证实,尤其是其分化状况,从分化良好、角蛋白珠突出的病变到缺乏此类结构的分化不良病变:现有文献阐明了中性粒细胞和巨噬细胞在角质珠蛋白降解过程中的作用,但多核巨细胞(MNGC)在这一过程中的参与仍是未知的:本研究报告了一例新病例,患者是一名 49 岁男性,患有中度分化的 OSCC,其特征是左侧口腔黏膜溃疡性生长。组织病理学分析显示,肿瘤细胞浸润、角质化和异常有丝分裂,同时大量异物和朗汉斯 MNGCs 使角蛋白珍珠降解。MNGCs在OSCC中错综复杂的角蛋白珠降解过程凸显了肿瘤的异质性和侵袭性,为手术、放疗和化疗策略提供了深刻的见解。外科医生必须慎重考虑这一过程,将其作为侵袭性行为的标志,并制定精确的手术计划和多学科方法,以获得最佳疗效:本病例强调了异物和朗汉斯MNGCs在OSCC内角蛋白珠降解过程中的关键作用,揭示了肿瘤生物学中迄今未被认识的一个方面。这一发现对了解 OSCC 的进展、预后和治疗反应性具有深远影响,值得进一步研究这一过程的分子机制。
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引用次数: 0
Evaluation of Efficacy of Aqua Titan Patch in Postoperative Sequelae After Lower Third Molar Surgery: A Prospective Study. Aqua-Titan贴片治疗下三磨牙术后后遗症的疗效评价:一项前瞻性研究
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 Epub Date: 2023-01-10 DOI: 10.1007/s12663-022-01845-9
Vertika Srivastava, D S Gupta, Neelima Gehlot, Nimish Agarwal, Samarth Johari

Objective: To evaluate the efficacy of aqua titan patch in postoperative sequelae after mandibular third molar surgery.

Material and methods: A total of 20 patients were selected and divided into two groups, Group A was evaluated by using Aqua titan patch with oral antibiotics and anti-inflammatory analgesics while Group B was only provided with antibiotics and anti-inflammatory analgesics.

Results: There were total 20 subjects, with 4 males and 16 females. Pain was evaluated after surgical removal, where significant reduction was observed on 5 and 7th postoperative day in study group with p value 0.004 and 0.013, respectively. Reduction in swelling was observed to be statistically highly significant (p values = 0.000) in study group on 5 and 7th postoperative days. Beneficial results were obtained in study group where mouth opening was statistically significant with p value 0.002 on 5th and 0.049 on 7th postoperative day. For postoperative neurosensory deficit, mean values were constant and difference was found to be statistically insignificant with p value 0.13.

Conclusion: Postoperative local application of aqua titan patch in study group provided beneficial effects in terms of reduction in pain, swelling and maximum mouth opening as compared to the control group.

目的:评估钛水贴对下颌第三磨牙手术后遗症的疗效:评估水钛贴对下颌第三磨牙手术后遗症的疗效:选取 20 名患者并将其分为两组,A 组在使用水钛贴片的同时口服抗生素和消炎镇痛药,B 组仅使用抗生素和消炎镇痛药:共有 20 名受试者,其中男性 4 人,女性 16 人。手术切除后对疼痛进行了评估,研究组在术后第 5 天和第 7 天的疼痛明显减轻,P 值分别为 0.004 和 0.013。研究组在术后第 5 天和第 7 天观察到肿胀明显减轻,P 值分别为 0.004 和 0.013。在研究组中,术后第 5 天和第 7 天的张口率分别为 0.002 和 0.049,具有统计学意义。在术后神经感觉缺失方面,平均值保持不变,差异无统计学意义,P 值为 0.13:与对照组相比,研究组术后局部贴敷钛酸水贴片在减轻疼痛、肿胀和最大张口度方面有良好效果。
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Journal of Maxillofacial & Oral Surgery
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