A. Muljačić, Matea Majstorović-Matejić, Marko Guberina, Ognjen Živković, R. Poljak-Guberina
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Prognostic Significance of Alkaline Phosphatase Activity and Callus Volume in Operatively Treated Bone Fractures
Total and bone alkaline phosphatase are indicators of bone formation, a process essential in bone healing. The aim of this study was to assess the relationship of both total and bone alkaline phosphatase with the course and features of healing in surgically treated long bone fractures as compared to the callus volume. In this study, total and bone alkaline phosphatase levels and the callus volume were measured in two patients with long bone fractures. Fracture healing was rapid in one patient and slow in the other. Depending on the healing outcome, on day 7 an increase in the case of slow healing and a decrease in the case of rapid healing was noted for both total and bone alkaline phosphatase. In the case of slow healing, the callus volume was significant whereas in the case of rapid healing the callus was almost invisible on day 7. This result indicates a possible prognostic significance of aforementioned clinical biochemical and radiographic parameters in the monitoring of long bone fracture healing.
期刊介绍：
International journal Collegium Antropologicum is the official journal of the Croatian Antropological Society and is jointly published by: Croatian Anthropological Society Croatian Association of Medical Anthropology - Croatian Medical Association Department of Natural Sciences, Anthropological Centre and the Scientific Council for Anthropological Research of the Croatian Academy of Sciences and Arts. With the numerous international recognition of co-operative experts, the Journal represents a relevant reference source in the fields of cultural and biological anthropology, sociology, ethnology, psychology, demography, history, archaeology, genetics, biomedicine, human ecology, nutrition and other fields related to multidisciplinary character of anthropology.
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