杉木(Caesalpinia sapan L.)的潜力乙醇提取物抗氧化和防晒

Mutista Hafshah, A. Rohmah, Ana Mardliyah
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引用次数: 2

摘要

虽然阳光对健康有很多好处,但长时间直接暴露在阳光下可能对皮肤有害。阳光照射的负面影响包括皮肤发红、晒伤、暗沉、皱纹、干燥、早衰以及皮肤癌。使用防晒霜来保护皮肤免受长时间阳光照射的有害影响正变得越来越普遍。另一方面,一些防晒霜含有潜在的有害化学物质,如异丙醇、DEA(二乙醇胺)、TEA(三乙醇胺)和MEA(单乙醇胺),长时间使用会引起过敏反应以及肾脏和肝脏疾病。因此,本研究旨在利用DPPH法测定天然成分,特别是杉木(Caesalpinia sappan L.)的抗氧化潜力,并利用紫外-可见分光光度法(Uv-Vis)进行体外SPF测试,以确定其作为防晒剂的潜力。结果表明,采用浸渍法提取的皂荚木乙醇提取率为17.779%。其IC50值为12611 mg/L,具有极强的抗氧化活性。此外,根据试验结果和SPF(防晒系数)值的计算,已显示出sapan木提取物具有作为防晒剂的潜力。使用提取物浓度为120 mg/L时,SPF值最高。
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Potential of Secang Wood (Caesalpinia sappan L.) Ethanol Extractas Anti-Oxidant and Sun-Protection
Although sunlight has numerous health benefits, prolonged direct exposure to the sun can be harmful to the skin. Among the negative effects of sun exposure are redness and burning of the skin, as well as dullness, wrinkles, dryness, and premature aging, as well as skin cancer. The use of sunscreen to protect the skin from the harmful effects of prolonged sun exposure is becoming more widespread. On the other hand, some sunscreens contain potentially harmful chemicals such as isopropyl alcohol, DEA (diethanolamine), TEA (triethanolamine), and MEA (monoethanolamine), which can cause allergic reactions as well as kidney and liver disorders when used for an extended period of time. As a result, this investigation was carried out in order to determine the antioxidant potential of natural ingredients, specifically sappan wood (Caesalpinia sappan L.), using the DPPH method, as well as its potential as a sun-protective agent using an in vitro SPF test using ultraviolet-visible (Uv-Vis) spectrophotometry (Uv-Vis). The results revealed that the maceration method produced a 17.779 percent yield of ethanol extract of sappan wood, which was used in this study. The extract possesses extremely potent antioxidant activity, as evidenced by its IC50 value of 12,611 mg/L. Furthermore, based on the results of tests and the calculation of the SPF (sun protection factor) value, sappan wood extract has been shown to have potential as a sun protection agent. Using an extract concentration of 120 mg/L, the highest SPF value.
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审稿时长
24 weeks
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