OSA患者声门上塌陷的外科治疗

Ido Amir, Hanna Gilat, U. Alkan
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引用次数: 0

摘要

阻塞性睡眠呼吸暂停(OSA)是一种常见的临床疾病,影响着全球数百万人。这种情况源于异常的解剖和生理特征,导致睡眠时间内上呼吸道间歇性塌陷。众所周知,如果不能及时正确诊断和治疗,OSA患者发生不良心血管后果的风险会增加。除了非侵入性治疗,如气道正压通气(PAP)面罩,几种手术方式已被证明可以成功降低上呼吸道塌陷的严重程度和频率。然而,由于不同的病理机制在每个患者病情的病理生理学中发挥作用,因此需要一种更个性化的方法。会厌塌陷是其中一种机制,目前尚待充分研究和理解。此外,关于会厌塌陷在OSA中的作用及其与不同治疗结果的关系的医学文献数量很少。在这篇文献综述中,我们的目的是介绍目前关于会厌塌陷的现有知识,它在OSA的病理生理学中的作用,以及与会厌塌陷相关的OSA的治疗。我们的结论是,需要进一步的研究,以制定关于当前问题的高质量循证临床指南。
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Surgery for Epiglottic Collapse in OSA Patients
Obstructive sleep apnea (OSA) is a common clinical entity, impacting millions of people worldwide. This condition stems from abnormal anatomical and physiological features, leading to intermittent upper airway collapse during sleeping hours. It has been well established that patients suffering from OSA are at increased risk for adverse cardiovascular outcomes if not properly diagnosed and treated in time. Aside from non-invasive treatments, such as positive airway pressure (PAP) masks, several surgical modalities have been shown to successfully reduce the severity and frequency of upper airway collapse. However, because different pathological mechanisms play a role in the pathophysiology of each patient’s condition, a more individualized approach is needed. One such mechanism is epiglottic collapse, which has been yet to be adequately studied and understood. Furthermore, the volume of medical literature addressing the role of epiglottic collapse in OSA and its association with different treatment outcomes is scarce. In this review of the literature, our aim was to present the current existing knowledge regarding epiglottic collapse, its role in the pathophysiology of OSA and the management of OSA associated with epiglottic collapse. We conclude that further research is needed in order to formulate quality evidence-based clinical guidelines regarding the issue at hand.
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来源期刊
Polish Otorhinolaryngology Review
Polish Otorhinolaryngology Review Medicine-Otorhinolaryngology
CiteScore
0.20
自引率
0.00%
发文量
23
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