自体肠浆液回输在新生儿肠造口术后的应用

Yajuan Xu, Ping Yan, Yanbo Wang, Wen-Chun Sun, Weibing Tang
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引用次数: 0

摘要

目的探讨自体肠浆液回输在新生儿肠造口术中的应用方法及价值。方法回顾性分析2010年1月至2017年12月南京医科大学儿童医院109例接受肠造口术的新生儿的临床资料。根据是否进行肠浆液回输将新生儿患者分为肠浆液回输组(63例新生儿)和对照组(46例新生儿)。收集新生儿患者90天体重增加、二期肠造口术年龄、术后停止静脉输注时间、二期肠造口术前再入院率。结果患儿肠造口距Treitz韧带的距离均为80 ~ 120 cm,两组间差异无统计学意义(P=0.42)。肠浆液回输组出生后90 d增重优于对照组(单腔组vs单腔对照组:[1.97±0.55]vs[1.50±0.57]kg, P=0.017;双流明组与双流明对照组:[1.82±0.49]vs。[1.48±0.65]kg, P=0.013),第二阶段肠造口闭合年龄(单腔组与单腔对照组:[115.76±15.85]∶[117.40±11.06]d, P=0.025;双腔组vs双腔对照组:[115.48±14.33]vs[126.03±8.85]d, P=0.001),术后停止静脉输注时间(单腔组vs单腔对照组:[14.24±3.30]vs[16.40±2.74]d, P=0.046;双腔组与双腔对照组:[15.07±3.65]d vs[18.71±3.63]d, P<0.01),二期肠造口前再入院率(单腔组与单腔对照组:9.5%[2/21]vs。20% (3/15), P = 0.337;双流明组vs双流明对照组:7.1%[3/42]vs。25.8% (8/31), P = 0.028)。结论自体肠浆液回输可改善小肠造口术后营养物质的吸收,改善远端肠管功能,为小肠连续性的早期恢复创造条件。关键词:新生儿;小肠造口;肠液回输
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Application of autologous succus entericus reinfusion after enterostomy in neonate
Objective To evaluate the application way and value of autologous succus entericus reinfusion in neonatal enterostomy. Methods Clinical data from 109 neonatal patients receiving enterostomy in Children's Hospital of Nanjing Medical University from January 2010 to December 2017 were retrospectively analyzed. The neonatal patients were divided into two groups according to whether succus entericus reinfusion conducted as succus entericus reinfusion group (63 neonatal patients) and control group (46 neonatal patients). The 90-day weight gain of the neonatal patients, age of the second stage enterostomy closure, cessation of intravenous infusion time after operation and the rate of re-admission before the second stage enterostomy closure were collected. Results The distance between enterostomy mouth and the Treitz ligament was 80-120 cm in all the children patients, and there was no significant difference between the two groups (P=0.42). The succus entericus reinfusion group was superior to the control group in the weight gain of 90 days after birth (single lumen group vs. single lumen control group: [1.97±0.55] vs. [1.50±0.57]kg, P=0.017; double lumens group vs. double lumens control group: [1.82±0.49]vs. [1.48±0.65] kg, P=0.013), age of the second stage enterostomy closure (single lumen group vs. single lumen control group: [115.76±15.85] vs. [117.40±11.06] d, P=0.025; double lumens group vs. double lumens control group: [115.48±14.33] vs. [126.03±8.85] d, P=0.001), cessation of intravenous infusion time after operation (single lumen group vs. single lumen control group: [ 14.24±3.30] vs. [16.40±2.74] d, P=0.046; double lumens group vs. double lumens control group: [15.07±3.65] vs. [18.71±3.63] d, P<0.01), and the rate of re-admission before the second stage enterostomy closure (single lumen group vs. single lumen control group: 9.5%[2/21]vs. 20%[3/15], P=0.337; double lumens group vs. double lumens control group: 7.1%[3/42]vs. 25.8%[8/31], P=0.028). Conclusion Autologous succus entericus reinfusion can improve the absorption of nutrients after the operation of small intestinal stoma, improve the function of the distal enteral tube, and create conditions for the early recovery of intestinal continuity. Key words: Neonate; Small intestine stoma; Succus entericus reinfusion
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来源期刊
中华临床营养杂志
中华临床营养杂志 Nursing-Nutrition and Dietetics
CiteScore
0.20
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2282
期刊介绍: The Chinese Journal of Clinical Nutrition was founded in 1993. It is the first professional academic journal (bimonthly) in my country co-sponsored by the Chinese Medical Association and the Chinese Academy of Medical Sciences to disseminate information on clinical nutrition support, nutrient metabolism, the impact of nutrition support on outcomes and "cost-effectiveness", as well as translational medicine and nutrition research. It is also a professional journal of the Chinese Medical Association's Parenteral and Enteral Nutrition Branch. The purpose of the Chinese Journal of Clinical Nutrition is to promote the rapid dissemination of knowledge on nutrient metabolism and the rational application of parenteral and enteral nutrition, focusing on the combination of multidisciplinary and multi-regional field investigations and clinical research. It mainly reports on nutritional risk screening related to the indications of parenteral and enteral nutrition support, "cost-effectiveness" research on nutritional drugs, consensus on clinical nutrition, guidelines, expert reviews, randomized controlled studies, cohort studies, glycoprotein and other nutrient metabolism research, systematic evaluation of clinical research, evidence-based case reports, special reviews, case reports and clinical experience exchanges, etc., and has a special column on new technologies related to the field of clinical nutrition and their clinical applications.
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