有精神病理的学生群体是否代表一般临床人群?强迫症的案例

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2023-04-01 DOI:10.1016/j.jocrd.2023.100807
Amitai Abramovitch , Anthony Robinson , Matthew J. Buckley , Demet Çek , Laura de Putter , Kiara R. Timpano
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引用次数: 1

摘要

一个长期存在的假设表明,大学生队列并不代表临床队列,因为学生被认为是“高功能”,这可能会限制可推广性。然而,很少有研究将学生中DSM障碍的情况与社区或寻求治疗样本中报告的情况进行比较,尤其是在强迫症(OCD)的情况下。为了填补文献中的这一空白,我们将大学生DSM强迫症的概况与寻求治疗和社区强迫症样本,以及患有其他DSM障碍或没有诊断的学生子样本进行了比较。来自两所美国大学和一所比利时大学的529名学生通过半结构化访谈进行了筛选,并完成了自我报告问卷。36名学生符合强迫症DSM标准。与非强迫症诊断(n=183)和非临床学生对照(n=311)的比较,在症状强迫症测量和共病特征方面产生了预期差异。与已发表的强迫症样本的比较得出了类似的结果。因此,学生的强迫症与临床样本中的强迫症相似,只是略有差异。我们得出的结论是,经过适当的筛查,学生是研究强迫症的可行人群。这可能会加强对强迫症的研究,使没有临床队列的研究人员能够为该领域做出贡献。
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Are student cohorts with psychopathology representative of general clinical populations? The case for OCD

A longstanding assumption suggests that college student cohorts are not representative of clinical cohorts as students are perceived as ‘high functioning’ which may limit generalizability. Yet little research has compared the profile of DSM disorders among students to those reported in community or treatment-seeking samples, particularly in the context of obsessive-compulsive disorder (OCD). To address this gap in the literature, we compared the profile of DSM OCD in college students, to treatment-seeking and community OCD samples, and student subsamples with other DSM disorders, or with no diagnosis. 529 students from two US and one Belgian university were screened using semi-structured interviews and completed self-report questionnaires. 36 students met DSM criteria for OCD. Comparison with non-OCD diagnoses (n = 183), and non-clinical student controls (n = 311) yielded expected differences on symptomatic OCD measures and comorbidity profiles. Comparisons with published OCD samples yielded a similar profile. Therefore, OCD in students is similar to OCD in clinical samples, with minor differences. We conclude that when appropriately screened, students are a viable population for the study of OCD. This may enhance research into OCD, allowing researchers without access to clinical cohorts to contribute to the field.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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