抗癌药物作用与恶性肿瘤综合治疗方案综述

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Galician Medical Journal Pub Date : 2022-06-01 DOI:10.21802/gmj.2022.2.7
N. Chrysanthakopoulos, E. Vryzaki
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引用次数: 0

摘要

癌症是全球数百万人死亡的主要原因,尽管分子生物学有所进步,但如何推进癌症治疗的问题仍然相关。癌症的研究必须专注于寻找新的、有效的化疗方案,以减轻传统治疗引起的严重副作用。现代技术目前正在临床试验中进行评估,或者已经被引入临床实践。目前癌症治疗的特点是无效和严重的副作用,以及在许多情况下缓解和治愈的希望。抗肿瘤药物和放射治疗已被用作某些癌症病例的首选治疗方法,但实体瘤除外。最近,免疫疗法已成为一种重要的治疗替代方案,在许多情况下,它是首选。这些疗法可以单独应用,也可以与其他药物联合应用。此外,基因治疗和纳米技术也是癌症治疗的有前景的方法。目前的综述介绍了癌症治疗的进展,从手术、化疗、放射和免疫治疗、基因治疗和纳米医学开始,重点介绍了最常见的抗癌药物和多种治疗方案。
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Anticancer Agent Effect and Polychemotherapy Regimens for Malignant Tumor Treatment - A Review
Cancer is a leading cause of millions of deaths worldwide and, despite the improvements in molecular biology, issues concerning how to advance cancer treatment are still relevant. Cancer research must be focused on finding new and efficient chemotherapeutic regimens that can relieve severe side effects caused by conventional treatments. Modern technologies are currently under estimation in clinical trials or have already been introduced into clinical practice. Nowadays cancer therapy is characterized by ineffectiveness and serious side effects, as well as by hope of remission and cure in many cases. Antitumor drugs and radiation have been used as the treatment of choice in some cancer cases, except for the choice of surgery in case of solid tumors. Recently, immunotherapy has emerged as a significant therapeutic alternative, and in many cases, it is the first choice. These therapies can be applied either alone or in combination with other agents. Additionally, gene treatment and nanotechnology are promising methods for cancer treatment as well. The current review presents the progress of cancer treatments, starting with surgery, chemotherapy, radiation and immunotherapy, gene treatment and nanomedicine, giving emphasis to the most common anticancer agents and polychemotherapeutic regimens.
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