{"title":"电纺柠檬木提取物负载伤口敷料通过抗炎和抗氧化活性促进糖尿病伤口愈合","authors":"Wenhua Ma, Zhongzhuang Pang, Yonglin Zhao","doi":"10.1166/jbn.2023.3632","DOIUrl":null,"url":null,"abstract":"In the current study, Morinda citrifolia extract was loaded into gelatin-based electrospun scaffolds to treat diabetic wounds. The produced scaffolds were characterized in vitro using electron microscopy, cell culture studies, antimicrobial assessment, tensile strength\n assay, and water uptake capacity measurements. Wound healing function of these dressings was evaluated in a rat model of diabetic wound. Study showed that Morinda citrifolia extract-loaded wound dressings promoted diabetic wound healing by increasing wound size reduction rate and collagen\n deposition.","PeriodicalId":15260,"journal":{"name":"Journal of biomedical nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Electrospun Morinda citrifolia Extract-Loaded Wound Dressings Promote Diabetic Wound Healing Through Antiinflammatory and Antioxidative Activities\",\"authors\":\"Wenhua Ma, Zhongzhuang Pang, Yonglin Zhao\",\"doi\":\"10.1166/jbn.2023.3632\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In the current study, Morinda citrifolia extract was loaded into gelatin-based electrospun scaffolds to treat diabetic wounds. The produced scaffolds were characterized in vitro using electron microscopy, cell culture studies, antimicrobial assessment, tensile strength\\n assay, and water uptake capacity measurements. Wound healing function of these dressings was evaluated in a rat model of diabetic wound. Study showed that Morinda citrifolia extract-loaded wound dressings promoted diabetic wound healing by increasing wound size reduction rate and collagen\\n deposition.\",\"PeriodicalId\":15260,\"journal\":{\"name\":\"Journal of biomedical nanotechnology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2023-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of biomedical nanotechnology\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1166/jbn.2023.3632\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biomedical nanotechnology","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1166/jbn.2023.3632","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
Electrospun Morinda citrifolia Extract-Loaded Wound Dressings Promote Diabetic Wound Healing Through Antiinflammatory and Antioxidative Activities
In the current study, Morinda citrifolia extract was loaded into gelatin-based electrospun scaffolds to treat diabetic wounds. The produced scaffolds were characterized in vitro using electron microscopy, cell culture studies, antimicrobial assessment, tensile strength
assay, and water uptake capacity measurements. Wound healing function of these dressings was evaluated in a rat model of diabetic wound. Study showed that Morinda citrifolia extract-loaded wound dressings promoted diabetic wound healing by increasing wound size reduction rate and collagen
deposition.
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