模拟婴儿胃的生化环境以评估婴儿配方食品的胃消化的挑战

IF 8.9 1区农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Current Opinion in Food Science Pub Date : 2023-04-01 DOI:10.1016/j.cofs.2022.100984

Xin Wang , Debashree Roy , Alejandra Acevedo-Fani , Aiqian Ye , Shikha Pundir , Harjinder Singh

{"title":"模拟婴儿胃的生化环境以评估婴儿配方食品的胃消化的挑战","authors":"Xin Wang , Debashree Roy , Alejandra Acevedo-Fani , Aiqian Ye , Shikha Pundir , Harjinder Singh","doi":"10.1016/j.cofs.2022.100984","DOIUrl":null,"url":null,"abstract":"<div><p>In infants, gastric digestion is a crucial step for the digestion and absorption of nutrients from infant formula, human milk, or any other milk substitutes. Critical understanding of the dynamics and biochemical conditions of the infant stomach is essential to improving the accuracy and reliability of <em>in vitro</em> models and guide the development of infant formulae that match the functional performance of human milk. This review discusses the current knowledge about infant gastric digestion gained from <em>in vitro</em>, <em>in vivo</em>, and human studies and learning from the digestion behavior of infant formulae. In particular, the current challenges when mimicking the gastric digestion processes in healthy infants are highlighted.</p></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"50 ","pages":"Article 100984"},"PeriodicalIF":8.9000,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Challenges in simulating the biochemical environment of the infant stomach to assess the gastric digestion of infant formulae\",\"authors\":\"Xin Wang , Debashree Roy , Alejandra Acevedo-Fani , Aiqian Ye , Shikha Pundir , Harjinder Singh\",\"doi\":\"10.1016/j.cofs.2022.100984\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>In infants, gastric digestion is a crucial step for the digestion and absorption of nutrients from infant formula, human milk, or any other milk substitutes. Critical understanding of the dynamics and biochemical conditions of the infant stomach is essential to improving the accuracy and reliability of <em>in vitro</em> models and guide the development of infant formulae that match the functional performance of human milk. This review discusses the current knowledge about infant gastric digestion gained from <em>in vitro</em>, <em>in vivo</em>, and human studies and learning from the digestion behavior of infant formulae. In particular, the current challenges when mimicking the gastric digestion processes in healthy infants are highlighted.</p></div>\",\"PeriodicalId\":54291,\"journal\":{\"name\":\"Current Opinion in Food Science\",\"volume\":\"50 \",\"pages\":\"Article 100984\"},\"PeriodicalIF\":8.9000,\"publicationDate\":\"2023-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Opinion in Food Science\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2214799322001862\",\"RegionNum\":1,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"FOOD SCIENCE & TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Food Science","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214799322001862","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}

引用次数: 2

摘要

在婴儿中，胃消化是消化和吸收婴儿配方奶粉、人乳或任何其他代用品中营养物质的关键步骤。对婴儿胃的动力学和生化条件的批判性理解对于提高体外模型的准确性和可靠性以及指导婴儿配方奶粉的开发与人乳的功能性能相匹配至关重要。本文综述了目前从体外、体内和人体研究中获得的关于婴儿胃消化的知识，以及从婴儿配方奶粉的消化行为中获得的知识。特别是，当前的挑战，当模仿健康婴儿的胃消化过程被强调。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Challenges in simulating the biochemical environment of the infant stomach to assess the gastric digestion of infant formulae

In infants, gastric digestion is a crucial step for the digestion and absorption of nutrients from infant formula, human milk, or any other milk substitutes. Critical understanding of the dynamics and biochemical conditions of the infant stomach is essential to improving the accuracy and reliability of in vitro models and guide the development of infant formulae that match the functional performance of human milk. This review discusses the current knowledge about infant gastric digestion gained from in vitro, in vivo, and human studies and learning from the digestion behavior of infant formulae. In particular, the current challenges when mimicking the gastric digestion processes in healthy infants are highlighted.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Current Opinion in Food Science Agricultural and Biological Sciences-Food Science

CiteScore

18.40

自引率

4.00%

发文量

157

审稿时长

92 days

期刊介绍： Current Opinion in Food Science specifically provides expert views on current advances in food science in a clear and readable format. It also evaluates the most noteworthy papers from original publications, annotated by experts. Key Features: Expert Views on Current Advances: Clear and readable insights from experts in the field regarding current advances in food science. Evaluation of Noteworthy Papers: Annotated evaluations of the most interesting papers from the extensive array of original publications. Themed Sections: The subject of food science is divided into themed sections, each reviewed once a year.