源自少突胶质细胞的肿瘤,一项为期五年的研究结果

Damian Lastra Copello
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摘要

目的:少突胶质细胞瘤是颅内肿瘤,占成人胶质瘤的5 - 25%。本研究回顾了2015年1月至2020年12月在“Hermanos Ameijeiras”医院治疗的少突胶质细胞瘤患者的治疗结果。方法:我们对在Hermanos Ameijeiras医院治疗的31例少突胶质细胞瘤患者进行观察性、描述性和回顾性研究型队列研究。结果:患者以男性为主,年龄在41 ~ 60岁之间(55%),临床表现为癫痫发作的占71%,额位占52%。根据Karnofsky功能量表(Karnofsky functional scale), 84%的患者进行了全手术切除,辅以辅助治疗,71%的患者疾病完全消退,100%的患者术后改善。结论:少突胶质细胞肿瘤是一种具有自身影像学、组织学和遗传学特征的胶质瘤。不同治疗方式的结合对疾病的控制及其生存具有重要作用,与术前和术后患者更好的神经功能状态相关
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Tumors of Oligodendroglial Origin, Results of a Five-Year Study
Objective: Oligodendrogliomas are intracranial tumors that represent between 5 to 25 % of gliomas in adults. This study reviews the results of treatment in patients with oligodendrogliomas treated at “Hermanos Ameijeiras” Hospital between January 2015 and December 2020. Methods: We made an observational, descriptive and retrospective study type cohort in a series of 31 patients with oligodendroglioma treated at “Hermanos Ameijeiras” Hospital. Results: Predominate male patients with ages between 41 to 60 years (55%), with clinical presentation of seizures in 71% and frontal location in 52%. Total surgical resection was performed in 84% of patient, which supported by adjunctive treatment, achieved total regression of disease in 71 % of patients and postoperative improvement in 100% of the patients according to the Karnofsky functional scale. Conclusions: Oligodendroglia tumors are gliomas with their own imaging, histological and genetic characteristics. Combination of the different therapeutic modalities has an important role in the control of the disease and its survival, associated with a better neurofunctional state of the patient in the pre-surgical and post-surgical period
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