This study examines the impact of Neuque n's pioneering Stroke Law in Argentina, focusing on its enactment and implementation. Neuque n, facing a high stroke incidence, established the first Argentinean legislation for stroke management, including prevention, acute treatment, and rehabilitation. The law led to the creation of the Provincial Stroke Network and inclusion of alteplase in the Neuque n Therapeutic Formulary. Results demonstrate advancements in healthcare delivery, with significant implications for public health policy and stroke management in Argentina. The study highlights challenges, particularly during the COVID-19 pandemic, and suggests future directions for comprehensive stroke care.
本研究探讨了 Neuque n 率先制定的《中风法》在阿根廷的影响，重点关注其颁布和实施情况。面对中风的高发病率，Neuque n 制定了阿根廷第一部有关中风管理的法律，包括预防、急性期治疗和康复。该法促成了省级中风网络的建立，并将阿替普酶纳入了 Neuque n 的治疗处方集。研究结果表明了医疗服务的进步，对阿根廷的公共卫生政策和中风管理具有重要意义。该研究强调了面临的挑战，尤其是在 COVID-19 大流行期间，并提出了全面中风治疗的未来方向。
{"title":"Impact of the Stroke Law in Neuquén. First Experience in Argentina","authors":"Vicente Miriam, Parada Gabriela, Hasdeu Santiago, Castro César, Orbea Lisandro, Albornoz Florencia","doi":"10.58624/svoane.2024.05.0146","DOIUrl":"https://doi.org/10.58624/svoane.2024.05.0146","url":null,"abstract":"This study examines the impact of Neuque n's pioneering Stroke Law in Argentina, focusing on its enactment and implementation. Neuque n, facing a high stroke incidence, established the first Argentinean legislation for stroke management, including prevention, acute treatment, and rehabilitation. The law led to the creation of the Provincial Stroke Network and inclusion of alteplase in the Neuque n Therapeutic Formulary. Results demonstrate advancements in healthcare delivery, with significant implications for public health policy and stroke management in Argentina. The study highlights challenges, particularly during the COVID-19 pandemic, and suggests future directions for comprehensive stroke care.","PeriodicalId":93502,"journal":{"name":"SVOA neurology","volume":" 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141831518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-17DOI: 10.58624/svoane.2024.05.0145
Fahad Albassam, Muneer Almutairi, Saleh Ahmed Alzaid
Vanishing White Matter Disease (VWM), also known as Childhood Ataxia with Central Nervous System Hypomyelination (CACH), although a rare neurological condition, is a prevalent hereditary leukoencephalopathy with a characteristic phenotype of gradual neurologic deterioration with ataxia being a prominent feature. It is characterized by a wide range of onset, from antenatal and infantile periods to early childhood and later adulthood periods. The early childhood form is considered the prevailing form, characterized by a preceding phase of normal development until the second or 3rd year of life, followed by progressive neurologic deterioration, accentuated by certain stressors, such as infections or minor trauma. Diagnosis is achieved based on the clinical pretext combined with distinctive MRI brain features, confirmed by DNA analysis detection of elf2B mutation. Our case is a healthy 18-month-old male who after a preceding upper respiratory tract infection, developed an ataxic gait, encephalopathy, and recurrent generalized seizures. Physical assessment revealed signs of generalized spasticity and hyperreflexia. Neuroimaging revealed diffuse symmetric supratentorial and infratentorial diffuse white matter hypomyelination. Interestingly, there was notable enhancement of the 3rd and 5th cranial nerves. Differential diagnosis included acute demyelinating leukoencephalopathies; and neuromatobolic disorders with acute presentations (including leukodystrophies, hypomyelinating disorders, and mitochondrial encephalopathies). In the early course of his management, he received immunomodulatory therapy in the form of pulse steroids, intravenous immunoglobulins, and oral tapering course of steroids. He had limited response to these interventions. Whole exome sequencing yielded a homozygous mutation in EIF2B3, confirming the diagnosis of VWMD/CACH. The presence of enhancing cranial neuropathies represent an atypical phenotype reported in other case reports and should alert the physician to avoid unnecessary intervention with immunosuppressive therapies.
{"title":"Early Childhood Onset Vanishing White Matter Disease with Multiple Cranial Nerve Enhancement: A New Consensus Criteria?","authors":"Fahad Albassam, Muneer Almutairi, Saleh Ahmed Alzaid","doi":"10.58624/svoane.2024.05.0145","DOIUrl":"https://doi.org/10.58624/svoane.2024.05.0145","url":null,"abstract":"Vanishing White Matter Disease (VWM), also known as Childhood Ataxia with Central Nervous System Hypomyelination (CACH), although a rare neurological condition, is a prevalent hereditary leukoencephalopathy with a characteristic phenotype of gradual neurologic deterioration with ataxia being a prominent feature. It is characterized by a wide range of onset, from antenatal and infantile periods to early childhood and later adulthood periods. The early childhood form is considered the prevailing form, characterized by a preceding phase of normal development until the second or 3rd year of life, followed by progressive neurologic deterioration, accentuated by certain stressors, such as infections or minor trauma. Diagnosis is achieved based on the clinical pretext combined with distinctive MRI brain features, confirmed by DNA analysis detection of elf2B mutation. Our case is a healthy 18-month-old male who after a preceding upper respiratory tract infection, developed an ataxic gait, encephalopathy, and recurrent generalized seizures. Physical assessment revealed signs of generalized spasticity and hyperreflexia. Neuroimaging revealed diffuse symmetric supratentorial and infratentorial diffuse white matter hypomyelination. Interestingly, there was notable enhancement of the 3rd and 5th cranial nerves. Differential diagnosis included acute demyelinating leukoencephalopathies; and neuromatobolic disorders with acute presentations (including leukodystrophies, hypomyelinating disorders, and mitochondrial encephalopathies). In the early course of his management, he received immunomodulatory therapy in the form of pulse steroids, intravenous immunoglobulins, and oral tapering course of steroids. He had limited response to these interventions. Whole exome sequencing yielded a homozygous mutation in EIF2B3, confirming the diagnosis of VWMD/CACH. The presence of enhancing cranial neuropathies represent an atypical phenotype reported in other case reports and should alert the physician to avoid unnecessary intervention with immunosuppressive therapies.","PeriodicalId":93502,"journal":{"name":"SVOA neurology","volume":" 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141831466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-17DOI: 10.58624/svoane.2024.05.0144
O. Uzoma, Havryliv Taras, Aigbogun Julia, Smolanka Andriy
The significant health burden caused by intra-axial brain lesions and the difficulties associated with their diagnosis and treatment have prompted a large number of researchers and practitioners to investigate various diagnostic and treatment modalities for their effectiveness and safety. This study focuses on evaluating different pre-, intra- and postoperative techniques and analyzes their advantages and limitations to ultimately improve the management of this type of brain lesion. Through a critical analysis of various scientific sources, this research aimed to synthesize existing knowledge on the topic. Magnetic resonance imaging plays a crucial role in diagnosing and managing brain tumors. Functional MRI identifies functional brain areas, but tumor-induced blood flow changes can affect its reliability. Connectome analysis provides information on functional localization and brain networks, which became possible using diffusion tensor imaging, that visualizes white matter pathways, aiding in tumor boundary delineation and surgical planning. Studies suggest this method can predict tumor histology and prognosis. Intraoperative MRI improves the extent of tumor resection and potentially patient survival. But due to its limitations it has alternative intraoperative techniques, like intraoperative ultrasound, fluorescence-guided surgery, direct electrical stimulation, deep brain stimulation, but evidence for most of these methods is limited for most brain tumors. Only ultrasound showed real-time tumor visualization and residual disease analysis offering high accuracy and is relatively inexpensive compared to ioMRI. This study can be useful to neurosurgeons, neuro-oncologists, neurologists, neuro-radiologists, and will demonstrate prospects for further research.
{"title":"Literature Review on Effective Use of Modern Modalities in Management of Intra-Axial Brain Lesions","authors":"O. Uzoma, Havryliv Taras, Aigbogun Julia, Smolanka Andriy","doi":"10.58624/svoane.2024.05.0144","DOIUrl":"https://doi.org/10.58624/svoane.2024.05.0144","url":null,"abstract":"The significant health burden caused by intra-axial brain lesions and the difficulties associated with their diagnosis and treatment have prompted a large number of researchers and practitioners to investigate various diagnostic and treatment modalities for their effectiveness and safety. This study focuses on evaluating different pre-, intra- and postoperative techniques and analyzes their advantages and limitations to ultimately improve the management of this type of brain lesion. Through a critical analysis of various scientific sources, this research aimed to synthesize existing knowledge on the topic. Magnetic resonance imaging plays a crucial role in diagnosing and managing brain tumors. Functional MRI identifies functional brain areas, but tumor-induced blood flow changes can affect its reliability. Connectome analysis provides information on functional localization and brain networks, which became possible using diffusion tensor imaging, that visualizes white matter pathways, aiding in tumor boundary delineation and surgical planning. Studies suggest this method can predict tumor histology and prognosis. Intraoperative MRI improves the extent of tumor resection and potentially patient survival. But due to its limitations it has alternative intraoperative techniques, like intraoperative ultrasound, fluorescence-guided surgery, direct electrical stimulation, deep brain stimulation, but evidence for most of these methods is limited for most brain tumors. Only ultrasound showed real-time tumor visualization and residual disease analysis offering high accuracy and is relatively inexpensive compared to ioMRI. This study can be useful to neurosurgeons, neuro-oncologists, neurologists, neuro-radiologists, and will demonstrate prospects for further research.","PeriodicalId":93502,"journal":{"name":"SVOA neurology","volume":" 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141829515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-11DOI: 10.58624/svoane.2024.05.0143
Ibrahim Kaleel, Ayoub Hambli, Abdel Salam Kaleel
A 51-year-old female presented with sudden onset of right-sided hemiparesis and aphasia. Imaging confirmed a left middle cerebral artery (MCA) territory infarct affecting the insular cortex. During her recovery, she developed excessive sweating exclusively on the right side of her body, leading to a diagnosis of contralateral hyperhidrosis. This case highlights the unusual presentation of hyperhidrosis following an MCA stroke and underscores the role of the insular cortex in autonomic regulation.
{"title":"Contralateral Hyperhidrosis After Large Acute Left MCA Territory Infarction: A Case Report","authors":"Ibrahim Kaleel, Ayoub Hambli, Abdel Salam Kaleel","doi":"10.58624/svoane.2024.05.0143","DOIUrl":"https://doi.org/10.58624/svoane.2024.05.0143","url":null,"abstract":"A 51-year-old female presented with sudden onset of right-sided hemiparesis and aphasia. Imaging confirmed a left middle cerebral artery (MCA) territory infarct affecting the insular cortex. During her recovery, she developed excessive sweating exclusively on the right side of her body, leading to a diagnosis of contralateral hyperhidrosis. This case highlights the unusual presentation of hyperhidrosis following an MCA stroke and underscores the role of the insular cortex in autonomic regulation.","PeriodicalId":93502,"journal":{"name":"SVOA neurology","volume":"92 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141657846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-10DOI: 10.58624/svoane.2024.05.0138
Sabina Oblitas López, Edgar Pinto Garcia, Mauro Toledo Aguirre
Medulloblastomas are WHO grade 4 embryonal neuroepithelial tumors that typically occur in the posterior fossa in the pediatric population. They represent 68% of embryonal tumors. The study of congenital cases is scarce due to the rarity of reported patients. There is also no specific bibliography, however histologically and molecularly they can be classified. On the other hand, due to the young age of these patients, they are difficult to manage and have a higher risk of complications in the treatment. In addition to this, patients are born with alterations in the development of the central nervous system due to chronic intracranial hypertension caused by said tumor and have little functional development. The objective of this study is to teach us to recognize the diagnosis early, the evolution of the disease to lead to better treatment for these patients in the future.
{"title":"Atypical Congenital Meduloblastoma: Case Report","authors":"Sabina Oblitas López, Edgar Pinto Garcia, Mauro Toledo Aguirre","doi":"10.58624/svoane.2024.05.0138","DOIUrl":"https://doi.org/10.58624/svoane.2024.05.0138","url":null,"abstract":"Medulloblastomas are WHO grade 4 embryonal neuroepithelial tumors that typically occur in the posterior fossa in the pediatric population. They represent 68% of embryonal tumors. The study of congenital cases is scarce due to the rarity of reported patients. There is also no specific bibliography, however histologically and molecularly they can be classified. On the other hand, due to the young age of these patients, they are difficult to manage and have a higher risk of complications in the treatment. In addition to this, patients are born with alterations in the development of the central nervous system due to chronic intracranial hypertension caused by said tumor and have little functional development. The objective of this study is to teach us to recognize the diagnosis early, the evolution of the disease to lead to better treatment for these patients in the future.","PeriodicalId":93502,"journal":{"name":"SVOA neurology","volume":" 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141128746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-02DOI: 10.58624/svoane.2024.05.0136
A. Kanodia, Aqeel Alameer, Riccardo Zannoni, Vilte Balcaityte, Jonathan O'Riordan
CLIPPERS is a rare inflammatory condition of the central nervous system. It is pathologically characterised by white matter perivascular lymphohistiocytic infiltrate with or without parenchymal extension. A male patient in mid sixties presented with dysarthria and facial numbness underwent an MRI brain which supported a diagnosis of a subacute posterior circulation infarct. The patient re-presented with worsening of symptoms and a repeat MRI revealed changes atypical for ischaemia and consistent with CLIPPERS. Our case represents a common presentation of a very rare condition.
{"title":"Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) Mimicking Posterior Circulation Infarction","authors":"A. Kanodia, Aqeel Alameer, Riccardo Zannoni, Vilte Balcaityte, Jonathan O'Riordan","doi":"10.58624/svoane.2024.05.0136","DOIUrl":"https://doi.org/10.58624/svoane.2024.05.0136","url":null,"abstract":"CLIPPERS is a rare inflammatory condition of the central nervous system. It is pathologically characterised by white matter perivascular lymphohistiocytic infiltrate with or without parenchymal extension. A male patient in mid sixties presented with dysarthria and facial numbness underwent an MRI brain which supported a diagnosis of a subacute posterior circulation infarct. The patient re-presented with worsening of symptoms and a repeat MRI revealed changes atypical for ischaemia and consistent with CLIPPERS. Our case represents a common presentation of a very rare condition.","PeriodicalId":93502,"journal":{"name":"SVOA neurology","volume":"18 39","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141019978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-04DOI: 10.58624/svoane.2024.05.0133
Noushin Mehrbod
Background: Artifact is a common error in patient’s electroencephalogram that if not addressed, it can lead to reduced quality and ultimately misdiagnosis. The aim of this study was to determine the frequency of different types of artifacts in electroencephalography of the brain of hospitalized and outpatient patients referred to the clinics of Al-Zahra Hospital and Khorshid Hospital in Isfahan. Methods: In this cross-sectional study that was performed in Al-Zahra and Noor hospitals in Isfahan in 1399, 256 patients were studied by electroencephalography and examined for their electroencephalography, the presence of physiological and non-physiological artifacts and the source of artifacts in them. Results: Out of 256 patients studied, in 237 cases (92.6%) the artifacts were physiological and 19 (7.4%) were non-physiological. The type of physiological artifacts included 217 cases (91.6%) ocular, 1 case (0.4%) cardiac, 5 cases (2.1%) sweating and 14 cases (5.9%) motor. Among non-physiological artifacts, 11 (57.9%) were electrode and 8 (42.1%) were external artifacts. There was no significant difference in the type of artifacts performed according to the age and sex of the patients. Conclusion: The findings of the present study show that the presence of artifacts in patient’s electroencephalogram is very common, and among them, physiological ocular artifacts and non-physiological electrode artifacts are the most common errors in patients’ electroencephalogram and therefore it is necessary to Investigate the possibility of different types of artifacts and take the necessary strategies to reduce them.
{"title":"Frequency of Different Types of Artifacts in Electroencephalography of the Brain of Hospitalized and Outpatient Patients Referred to the Clinics of Al-Zahra Hospital and Khorshid Hospital in Isfahan","authors":"Noushin Mehrbod","doi":"10.58624/svoane.2024.05.0133","DOIUrl":"https://doi.org/10.58624/svoane.2024.05.0133","url":null,"abstract":"Background: Artifact is a common error in patient’s electroencephalogram that if not addressed, it can lead to reduced quality and ultimately misdiagnosis. The aim of this study was to determine the frequency of different types of artifacts in electroencephalography of the brain of hospitalized and outpatient patients referred to the clinics of Al-Zahra Hospital and Khorshid Hospital in Isfahan. Methods: In this cross-sectional study that was performed in Al-Zahra and Noor hospitals in Isfahan in 1399, 256 patients were studied by electroencephalography and examined for their electroencephalography, the presence of physiological and non-physiological artifacts and the source of artifacts in them. Results: Out of 256 patients studied, in 237 cases (92.6%) the artifacts were physiological and 19 (7.4%) were non-physiological. The type of physiological artifacts included 217 cases (91.6%) ocular, 1 case (0.4%) cardiac, 5 cases (2.1%) sweating and 14 cases (5.9%) motor. Among non-physiological artifacts, 11 (57.9%) were electrode and 8 (42.1%) were external artifacts. There was no significant difference in the type of artifacts performed according to the age and sex of the patients. Conclusion: The findings of the present study show that the presence of artifacts in patient’s electroencephalogram is very common, and among them, physiological ocular artifacts and non-physiological electrode artifacts are the most common errors in patients’ electroencephalogram and therefore it is necessary to Investigate the possibility of different types of artifacts and take the necessary strategies to reduce them.","PeriodicalId":93502,"journal":{"name":"SVOA neurology","volume":"82 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140742439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-06DOI: 10.58624/svoane.2024.05.0130
Neda Kamandi
Spinal fusion is a common and effective option for patients with symptomatic degenerative disc disorders. However, concerns have raised over the probability of adjacent segment degeneration (ASDe) and adjacent segment disease (ASDi) following spinal instrumentation. Current study sought to document evidence on the incidence of ASDe and ASDi after lumbar fusion surgery and the risk factors precipitating adjacent pathologies. Given the benefits of spinal fusion surgery, it remains unclear whether adjacent pathologies are attributed to the natural degeneration or the adjacent fusion.
{"title":"Adjacent Segment Degeneration and Adjacent Segment Disease: Implications following Spinal Fusion Surgery","authors":"Neda Kamandi","doi":"10.58624/svoane.2024.05.0130","DOIUrl":"https://doi.org/10.58624/svoane.2024.05.0130","url":null,"abstract":"Spinal fusion is a common and effective option for patients with symptomatic degenerative disc disorders. However, concerns have raised over the probability of adjacent segment degeneration (ASDe) and adjacent segment disease (ASDi) following spinal instrumentation. Current study sought to document evidence on the incidence of ASDe and ASDi after lumbar fusion surgery and the risk factors precipitating adjacent pathologies. Given the benefits of spinal fusion surgery, it remains unclear whether adjacent pathologies are attributed to the natural degeneration or the adjacent fusion.","PeriodicalId":93502,"journal":{"name":"SVOA neurology","volume":"49 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140260789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-16DOI: 10.58624/svoane.2024.05.0129
Maikel Germán Correa Sánchez
Diseases of the nervous system are sometimes confined to the spinal cord, and there they give rise to peculiar syndromes that depend on the special physiological and anatomical characteristics of that organ. On the other hand, spinal arteries do not tend to show atherosclerosis and emboli rarely lodge in them, giving rise to vascular diseases (1%) where infarctions occur with some regularity at this level. The most common clinical presentation is anterior spinal artery syndrome, a sudden-onset pathology with neurological involvement and devastating and disabling consequences for the affected patient. Its manifestations vary depending on the level of occlusion in the affected area. We present the case of a 74-year-old female patient, who was admitted due to sudden loss of muscle strength in both lower limbs, with a timely diagnosis achieved through clinical and magnetic resonance imaging of the dorsolumbar spine.
{"title":"Spinal Infarction: Anterior Spinal Artery Syndrome. Presentation of a Clinical Case","authors":"Maikel Germán Correa Sánchez","doi":"10.58624/svoane.2024.05.0129","DOIUrl":"https://doi.org/10.58624/svoane.2024.05.0129","url":null,"abstract":"Diseases of the nervous system are sometimes confined to the spinal cord, and there they give rise to peculiar syndromes that depend on the special physiological and anatomical characteristics of that organ. On the other hand, spinal arteries do not tend to show atherosclerosis and emboli rarely lodge in them, giving rise to vascular diseases (1%) where infarctions occur with some regularity at this level. The most common clinical presentation is anterior spinal artery syndrome, a sudden-onset pathology with neurological involvement and devastating and disabling consequences for the affected patient. Its manifestations vary depending on the level of occlusion in the affected area. We present the case of a 74-year-old female patient, who was admitted due to sudden loss of muscle strength in both lower limbs, with a timely diagnosis achieved through clinical and magnetic resonance imaging of the dorsolumbar spine.","PeriodicalId":93502,"journal":{"name":"SVOA neurology","volume":"283 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140453957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-30DOI: 10.58624/svoane.2024.05.0128
Charles Ce Wang
A 22-year-old woman presented to the emergency department (ED) on two occasions with seizures, altered mental status, psychoses, and behavioral changes. Analysis of both serum and cerebrospinal fluid revealed positive anti-NMDA receptor (NMDAR) antibodies, confirming the diagnosis of NMDAR antibody encephalitis. Interestingly, 5-6 weeks before her ED visits, she had experienced a SARS-CoV-2 infection, potentially serving as a triggering factor for her autoimmune encephalitis. This case adds to the limited instances documented in the literature, highlighting the potential link between SARS-CoV-2 infection and the onset of autoimmune encephalitis
{"title":"A 22-Year-Old Woman with NMDA Receptor Antibody Encephalitis Possibly Triggered by SARS-CoV-2 Infection","authors":"Charles Ce Wang","doi":"10.58624/svoane.2024.05.0128","DOIUrl":"https://doi.org/10.58624/svoane.2024.05.0128","url":null,"abstract":"A 22-year-old woman presented to the emergency department (ED) on two occasions with seizures, altered mental status, psychoses, and behavioral changes. Analysis of both serum and cerebrospinal fluid revealed positive anti-NMDA receptor (NMDAR) antibodies, confirming the diagnosis of NMDAR antibody encephalitis. Interestingly, 5-6 weeks before her ED visits, she had experienced a SARS-CoV-2 infection, potentially serving as a triggering factor for her autoimmune encephalitis. This case adds to the limited instances documented in the literature, highlighting the potential link between SARS-CoV-2 infection and the onset of autoimmune encephalitis","PeriodicalId":93502,"journal":{"name":"SVOA neurology","volume":"162 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140481892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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