{"title":"海洋大环内酯类药物的潜在应用：来自海洋的新药？","authors":"M. Gammone, N. D’Orazio","doi":"10.22034/IAR(20).2020.1898824.1048","DOIUrl":null,"url":null,"abstract":"The sea is an untapped and unexploited wide ecosystem, which results to be extremely rich in diverse species: marine organisms are a source of many compounds and substances with numerous biological activities. Important marine biologically active molecules are, among others, macrolides, which could become the source of new and effective medicaments and therapeutics, due to their potential anti-inflammatory, antimicrobial (not only antibacterial and antifungal, but also antiprotozoal and antiviral), antioxidant, immunomodulant and antitumor capacities. Aim of this review is to examine the biological activities and the potential clinical and pharmaceutical applications of these interesting and fascinating novel marine bioactive compounds.","PeriodicalId":13619,"journal":{"name":"International Aquatic Research","volume":" ","pages":""},"PeriodicalIF":1.4000,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Potential applications of marine macrolides: New drugs from the sea?\",\"authors\":\"M. Gammone, N. D’Orazio\",\"doi\":\"10.22034/IAR(20).2020.1898824.1048\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The sea is an untapped and unexploited wide ecosystem, which results to be extremely rich in diverse species: marine organisms are a source of many compounds and substances with numerous biological activities. Important marine biologically active molecules are, among others, macrolides, which could become the source of new and effective medicaments and therapeutics, due to their potential anti-inflammatory, antimicrobial (not only antibacterial and antifungal, but also antiprotozoal and antiviral), antioxidant, immunomodulant and antitumor capacities. Aim of this review is to examine the biological activities and the potential clinical and pharmaceutical applications of these interesting and fascinating novel marine bioactive compounds.\",\"PeriodicalId\":13619,\"journal\":{\"name\":\"International Aquatic Research\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2020-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Aquatic Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22034/IAR(20).2020.1898824.1048\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MARINE & FRESHWATER BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Aquatic Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22034/IAR(20).2020.1898824.1048","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MARINE & FRESHWATER BIOLOGY","Score":null,"Total":0}
Potential applications of marine macrolides: New drugs from the sea?
The sea is an untapped and unexploited wide ecosystem, which results to be extremely rich in diverse species: marine organisms are a source of many compounds and substances with numerous biological activities. Important marine biologically active molecules are, among others, macrolides, which could become the source of new and effective medicaments and therapeutics, due to their potential anti-inflammatory, antimicrobial (not only antibacterial and antifungal, but also antiprotozoal and antiviral), antioxidant, immunomodulant and antitumor capacities. Aim of this review is to examine the biological activities and the potential clinical and pharmaceutical applications of these interesting and fascinating novel marine bioactive compounds.
期刊介绍：
The journal (IAR) is an international journal that publishes original research articles, short communications, and review articles in a broad range of areas relevant to all aspects of aquatic sciences (freshwater and marine). The Journal specifically strives to increase the knowledge of most aspects of applied researches in both cultivated and wild aquatic animals in the world. The journal is fully sponsored, which means it is free of charge for authors. The journal operates a single-blind peer review process. The main research areas in aquatic sciences include: -Aquaculture- Ecology- Food science and technology- Molecular biology- Nutrition- Physiology- Water quality- Climate Change
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