Epidemiology of tuberculosis combined with HIV infection, in the constituent entities of the Russian Federation with a low rate of tuberculosis prevalence

Objective. Analysis of the main epidemiological indicators characterizing the situation of tuberculosis combined with HIV infection in the Kaluga region for the period from 2015 to 2019.Materials and methods. For the analysis, was used information on 1159 newly diagnosed patients with tuberculosis, those who arenot infected with HIV infection, and 106 newly diagnosed patients with tuberculosis combined with HIV infection in the Kaluga region for the period from 2015 to 2020.Results. In the constituent entities of the Russian Federation, where the incidence of tuberculosis is declining annually, the registration of cases of tuberculosis combined with HIV infection is due to the spread of tuberculosis among HIV-infected contingents registered in AIDS centers.The main reasons for this situation are the late detection of tuberculosis among patients with HIV infection, when the course of the disease becomes widespread and low adherenceofpatients with HIV infectionto treatment antiretroviral drugs.