扁平地衣的角化变型或扁平地衣伴角化变型:一个具有挑战性的病例报告

H. Eftekhari, R. Rafiei, Kaveh Gharaienejad, Behnam Rafiee
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引用次数: 1

摘要

环状苔藓样病变有许多鉴别诊断。扁平苔藓(Lichen planus, LP)和多孔角化症可表现为环状病变,伴地衣样组织浸润,但典型的角膜片状形成主要有利于多孔角化症。我们报告一个57岁的男性,在小腿上有丘疹泡状和环状病变,并伴有左大趾甲外生性病变。丘疹病变表现为LP的典型组织病理学,但环状病变显示不完全的角膜片状形成,可见于LP的多孔性角化变体。甲床活检显示原位鳞状细胞癌,因此进行远端指骨截肢。我们的病人对局部和全身类固醇没有很好的反应,但口服类维甲酸有中度改善。我们认为我们的病例有不同类型的LP,包括经典的,大疱性和角化变孔,这是一种罕见的关联。
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Porokeratotic variant of lichen planus or lichen planus with porokeratosis: report of a challenging case
Annular lichenoid diseases have many differential diagnoses. Lichen planus (LP) and porokeratosis could show annular-shaped lesions with a lichenoid tissue pattern infiltration, but typical cornoid lamella formation is mainly in favor of porokeratosis. We present a 57-year-old man with papulovesicular and annular lesions on the shins with an exophytic lesion of left great toe nail. Papular lesions showed classic histopathology of LP, but annular lesions revealed imperfect cornoid lamella formation that could be seen in the porokeratotic variant of LP. Nail bed biopsy showed in-situ squamous cell carcinoma and so distal phalangeal amputation was performed. Our patient had no good response to topical and systemic steroid, but he had moderate improvement with oral retinoid. We think that our case had different types of LP including classic, bullous and porokeratotic variants which is a rare association.
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来源期刊
CiteScore
0.50
自引率
0.00%
发文量
0
审稿时长
17 weeks
期刊介绍: The Journal of The Egyptian Women''s Dermatologic Society (JEWDS) was founded by Professor Zenab M.G. El-Gothamy. JEWDS is published three times per year in January, May and September. Original articles, case reports, correspondence and review articles submitted for publication must be original and must not have been published previously or considered for publication elsewhere. Their subject should pertain to dermatology or a related scientific and technical subject within the field of dermatology.
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