在高脂肪饮食诱导的肥胖条件下,即使在骨骼肌没有肥大的情况下,力量训练也能减少脂肪积累并改善血脂状况

IF 3.8 Q2 ENDOCRINOLOGY & METABOLISM Journal of Obesity Pub Date : 2020-11-20 DOI:10.1155/2020/8010784
C. Contreiro, L. C. Caldas, B. Nogueira, A. Leopoldo, A. P. Lima-Leopoldo, L. Guimarães‐Ferreira
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引用次数: 2

摘要

目的是研究力量训练对喂食不饱和高脂肪饮食(HFD)的肥胖大鼠骨骼肌形态和代谢适应的影响。假设是力量训练诱导肥胖大鼠积极的代谢适应,尽管受损的肌肉肥大。雄性Wistar大鼠(n = 58)随机分为两组,分别饲喂含脂肪49.2%的高脂日粮和标准日粮。在诱导和维持肥胖后,将大鼠分为四组:久坐对照组(CS)、力量训练方案对照组(CT)、肥胖久坐组(ObS)和肥胖力量训练方案组(ObT)。运动方案包括在垂直梯子上进行10周的训练(每周三次),并在动物的尾巴上固定重物。在10周结束时,力量训练促进了肥胖动物的身体组成和代谢参数的积极变化。具体来说,与ObS相比,ObT动物的体脂和肥胖指数分别降低了22.6%和14.3%。此外,这些大鼠的甘油三酯(ObT = 23.1±9.5比ObS = 30.4±6.9 mg/dL)和瘦素(ObT = 13.2±7.2比ObS = 20.5±4.3 ng/mL)水平较低。与各自的对照组相比,训练(ObT和CT)诱导了更大的力量增加。此外,ObT组幻觉长屈肌(FHL)的重量高于CT组,增加了26.1%。然而,训练并没有促进肥大,正如FHL和足底肌肉相似的横截面积所观察到的那样。基于这些结果,高强度力量训练促进了喂食高脂肪饮食而不适应骨骼肌的肥胖大鼠的身体组成和代谢谱的改善,成为治疗肥胖的相关补充策略。
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Strength Training Reduces Fat Accumulation and Improves Blood Lipid Profile Even in the Absence of Skeletal Muscle Hypertrophy in High-Fat Diet-Induced Obese Condition
The aim was to investigate the effect of strength training on skeletal muscle morphology and metabolic adaptations in obese rats fed with unsaturated high-fat diet (HFD). The hypothesis was that strength training induces positive metabolic adaptations in obese rats despite impaired muscle hypertrophy. Male Wistar rats (n = 58) were randomized into two groups and fed a standard diet or a high-fat diet (HFD) containing 49.2% of fat. After induction and maintenance to obesity, the rats were divided into four groups: animals distributed in sedentary control (CS), control submitted to strength training protocol (CT), obese sedentary (ObS), and obese submitted to strength training protocol (ObT). The exercise protocol consisted of 10 weeks of training on a vertical ladder (three times a week) with a load attached to the animal’s tail. At the end of 10 weeks, strength training promoted positive changes in the body composition and metabolic parameters in obese animals. Specifically, ObT animals presented a reduction of 22.6% and 14.3% in body fat and adiposity index when compared to ObS, respectively. Furthermore, these rats had lower levels of triglycerides (ObT = 23.1 ± 9.5 vs. ObS = 30.4 ± 6.9 mg/dL) and leptin (ObT = 13.2 ± 7.2 vs. ObS = 20.5 ± 4.3 ng/mL). Training (ObT and CT) induced a greater strength gain when compared with the respective control groups. In addition, the weight of the flexor hallucis longus (FHL) muscle was higher in the ObT group than in the CT group, representing an increase of 26.1%. However, training did not promote hypertrophy as observed by a similar cross-sectional area of the FHL and plantar muscles. Based on these results, high-intensity strength training promoted an improvement of body composition and metabolic profile in obese rats that were fed a high-fat diet without skeletal muscle adaptations, becoming a relevant complementary strategy for the treatment of obesity.
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来源期刊
Journal of Obesity
Journal of Obesity ENDOCRINOLOGY & METABOLISM-
CiteScore
7.50
自引率
3.00%
发文量
19
审稿时长
21 weeks
期刊介绍: Journal of Obesity is a peer-reviewed, Open Access journal that provides a multidisciplinary forum for basic and clinical research as well as applied studies in the areas of adipocyte biology & physiology, lipid metabolism, metabolic syndrome, diabetes, paediatric obesity, genetics, behavioural epidemiology, nutrition & eating disorders, exercise & human physiology, weight control and health risks associated with obesity.
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