埃塞俄比亚西南部Jimma健康中心抗生素使用及相关问题评估

Kinati Terfa Geremew, Zeleke Gemechu
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引用次数: 0

摘要

滥用抗生素是耐药性发展的主要原因。本研究的目的是评估Jimma健康中心的抗生素使用模式和相关问题。该研究于2016年2月25日至2016年3月25日进行。为了对处方指标进行回顾性分析,从卫生中心登记部门(2015年3月8日至2016年3月25日)的9800张病历表中系统选择了295张符合纳入标准的病历表。对120名患者进行了前瞻性访谈。每次用药的平均次数为2.2次,使用抗生素的比例为32%。98.9%的药物是用它们的通用名称开的,注射次数为9%。阿莫西林是研究期间常用的抗生素(26%)。平均会诊和配药时间分别为5.1和1.3分钟,73%的配药药物都有充分的标签。有一份埃塞俄比亚基本药物清单和标准治疗指南(STG-2014)。研究期间没有药物处方,一些抗生素也不可用。这项研究的结果显示,处方做法和每张处方的平均药物数量与世界卫生组织的标准略有偏差。但非专利和注射处方以及埃塞俄比亚基本药物清单的使用并不是问题。
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Assessment of antibiotics use and associated problems at Jimma Health Center, South West Ethiopia
Misuse of antibiotics is the main cause for resistance development. The objective of this study is to assess patterns of antibiotics use and associated problems at Jimma Health Center. The study was conducted from February 25, 2016 to March 25, 2016. For the analysis of prescribing indicators retrospectively 295 patient charts that fulfills inclusion criteria were systematically selected from a total of 9800 charts from the health center registry department (from March 8, 2015 to March 25, 2016). Prospectively 120 patients were interviewed. The average number of drugs per encounter was 2.2 and percentage of encounter with antibiotics was 32%. 98.9% of medication was prescribed by their generic name and injection encounter was 9%. Amoxicillin was a commonly prescribed antibiotic during the study period (26%). The average consultation and dispensing time were 5.1 and 1.3 min, respectively and 73% of drugs dispensed were adequately labeled. There was a copy of Ethiopian essential drug list and standard treatment guidelines (STG - 2014). There was no drug formulary during the study period and some antibiotics were not available. Result of this study revealed prescribing practices and average number of drugs per prescription slightly deviate from World Health Organization standard. But generic and injection prescribing as well as use of Ethiopian essential drug list was not a problem.
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