不确定的树突状细胞肿瘤(IDCT)

Q4 Medicine Vestnik dermatologii i venerologii Pub Date : 2023-09-06 DOI:10.25208/vdv8137
Evgenia V. Okladnikova, Vladimir M. Merk, Yuriy А. Krivopalov, Vladimir A. Khorzhevskii, Tatiana Ruksha
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引用次数: 0

摘要

不确定树突状细胞瘤(IDCT)是一种罕见的组织细胞肿瘤,其特征是不确定的树突状细胞增殖。它更常见于中年人,在男性和女性中的比例大致相等。IDCT的病因尚不清楚。与其他类似IDCT的疾病进行鉴别诊断,对确定治疗策略很重要。本文介绍了一例48岁男性IDCT的临床病例,仅凭患者的主诉和检查数据不足以诊断该疾病。IDCT中的皮肤表现与其他皮肤病理的相似性需要对受影响区域进行免疫组织化学研究,以评估CD1a、CD68、S100、Langerin的表达,以及是否存在Birbeck颗粒粘液化。常规组织学检查不足以进行正确的IDCT诊断。
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Indeterminate dendritic cell tumor (IDCT)
Indeterminate dendritic cell tumor (IDCT) is rare histiocytic tumor characterized by the proliferation of indeterminate dendritic cells. It is more often diagnosed in middle-aged people, in approximately equal proportions in men and women. The etiology of IDCT is unknown. Differential diagnosis is carried out with other diseases that mimic IDCT and is important for determining treatment tactics. The present paper presents a clinical case of IDCT in a 48-year-old man. Using only the patient's complaints and examination data was not enough to diagnose the disease. The similarity of skin manifestations in IDCT with other skin pathologies requires an immunohistochemical study of the affected areas for CD1a, CD68, S100, Langerin expression evaluation as well as the presence of Birbeck's granules visulization. Routine histological examination does not sufficient for correct IDCT diagnostics.
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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
40
审稿时长
8 weeks
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