艾滋病毒传播危险因素指南存在冲突

Jiman He
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引用次数: 2

摘要

根据目前的指导方针,将粘膜暴露在HIV感染者的血液和体液中有传播的风险。大约30%-80%的艾滋病毒感染者至少有一种口腔表现。最常见的口腔表现(伪膜性念珠菌感染、线形牙龈红斑等)会自发或刺激后出血,口交和深吻过程中的剧烈搅拌会增加口腔表现出血的风险,使伴侣的口腔和生殖器粘膜暴露在血液中。然而,目前的指导方针声称,口交和深吻几乎没有感染艾滋病毒的风险。这些指导方针相互冲突,表明目前基于这些指导方针的预防战略存在潜在问题。在讨论了有关动物、女同性恋者、年轻人和职业暴露的现有数据后,本文认为,当一方出现与HIV相关的口腔出血表现时,口交和深吻是危险因素,而与口交和深吻相关的感染人数是显著的。应紧急重新评估当前关于艾滋病毒风险因素的指南,并以开放的心态进行新的研究,以探索风险因素。
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Guidelines on Risk Factors for HIV Transmission Are Conflicting
According to current guidelines, exposing mucous membrane to blood and body fluids of HIV infected people is risk of transmission. About 30% - 80% of HIV infected people have at least one oral manifestation. The most frequently occurring oral manifestations (pseudomembranous candidiasis, linear gingival erythema, etc.) give rise to bleeding either spontaneously or after stimulation, and strenuous stirring during oral sex and deep-mouth kissing increase risk of bleeding from oral manifestations, exposing oral and genital mucous membrane of partners to the blood. However, current guidelines assert that there’s little to no risk of getting HIV from oral sex and deep-mouth kissing. These guidelines are conflict with each other, suggesting potential problems with current prevention strategies which are based on the guidelines. After discussing existing data on animals, lesbians, young peoples, and occupational exposures, this paper suggests oral sex and deep-mouth kissing are risk factors when one partner has HIV-associated oral bleeding manifestations, and the number of infections associated with oral sex and deep-mouth kissing is significant. Current guidelines on HIV risk factors should be reevaluated urgently, and new studies should be undertaken with an open mind to explore risk factors.
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