[老年患者双头关节成形术后的急性术后感染]。

Unfallchirurgie (Heidelberg, Germany) Pub Date : 2024-02-01 Epub Date: 2023-10-18 DOI:10.1007/s00113-023-01376-z
Susanne Baertl, Nora Renz, Volker Alt, Carsten Perka, Stephanie Kirschbaum
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引用次数: 0

摘要

双头关节成形术后的急性假体周围关节感染(PJI)是一个主要挑战,在大多数多发病的老年患者群体中,1年死亡率高达50%。由于术前患者优化的可能性有限,据报道感染率高达9%,明显高于选择性关节成形术。由于研究情况的异质性和缺乏前瞻性随机研究,治疗金标准尚未建立。目前最有前景的治疗选择似乎是单阶段干细胞置换术结合杯状假体植入(转换为全髋关节置换术,感染根除率高达100%)。单独使用桥接、抗生素和植入物保留(DAIR)的方法显示出明显较差的成功率(16-82%)。手术治疗后应始终进行抗生素治疗,总持续时间为12周。除了已确定的围手术期抗生素预防外,在预防双头关节成形术中PJI方面,抗生素负载骨水泥的使用似乎优于非骨水泥柄固定。
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[Acute postoperative infections after dual head arthroplasty in geriatric patients].

Acute periprosthetic joint infections (PJI) after dual head arthroplasty represent a major challenge with a 1-year mortality rate up to 50% in the mostly multimorbid geriatric patient collective. Due to the limited possibilities of preoperative patient optimization, infection rates of up to 9% have been reported, which is significantly higher than in elective arthroplasty. A therapeutic gold standard has not yet been established due to the heterogeneous study situation and the lack of prospective randomized studies. The most promising therapeutic option currently appears to be a single-stage stem replacement in combination with implantation of a cup component (conversion to total hip arthroplasty, infection eradication in up to 100%). An approach of débridement, antibiotics, implant retention (DAIR) alone shows significantly poorer success rates (16-82%). Surgical treatment should always be followed by antibiotic treatment with a total duration of 12 weeks. In addition to the established perioperative antibiotic prophylaxis, the use of antibiotic-loaded bone cement seems to be superior to cementless stem fixation in preventing PJI in dual head arthroplasty.

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