鼻腔空细胞异位垂体腺瘤。

IF 0.4 Q4 OTORHINOLARYNGOLOGY Case Reports in Otolaryngology Pub Date : 2023-10-12 eCollection Date: 2023-01-01 DOI:10.1155/2023/5561092
Nicholas Figaro, Jibran Juman, Ashton Ramsundar, Fidel Rampersad, Melanie Johncilla, Solaiman Juman
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摘要

异位垂体腺瘤(EPA)是一种不常见的垂体腺瘤,仅占所有垂体腺瘤的2%。EPAs是一种良性肿瘤,可以发生在垂体胚胎迁移路径上的任何地方,与鞍内元件无关。它们通常具有激素活性,并以女性为主。EPAs的临床特征高度依赖于其激素活性、解剖位置和局部质量效应。适当的放射学成像对于评估EPA至关重要。影像学检查显示垂体和鞍区正常,提供了肿瘤大小、边缘和范围的详细信息,并有助于制定手术计划。诊断异位垂体腺瘤的标准取决于详细的组织病理学检查。环保局的管理应该是个性化的。我们报告一例71岁男性患者,他有9个月的左鼻阻塞、脓性鼻腔分泌物和间歇性前鼻出血病史。这名患者由他的全科医生治疗慢性鼻窦炎,但由于症状未能缓解,他去看了耳鼻喉科医生。通过对活检标本的组织学分析,该患者被诊断为无细胞异位垂体腺瘤,活检标本显示腺垂体细胞没有细胞类型特异性分化。患者随后接受了鼻内镜下鼻内切除术,并顺利住院。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Null-Cell Ectopic Pituitary Adenoma of the Nasal Cavity.

An ectopic pituitary adenoma (EPA) is an uncommon type of pituitary adenoma, accounting for only 2% of all pituitary adenomas. EPAs are benign tumors that can occur anywhere along the migratory embryonic path of the pituitary gland and have no relationship to intrasellar elements. They are usually hormonally active and have a minor female predominance. The clinical features of EPAs are highly dependent on its hormonal activity, anatomical location, and its local mass effect. Appropriate radiological imaging is essential for the evaluation of EPAs. Imaging investigations show a normal pituitary gland and sellar turcica, provide details on the size of the tumor, its margins, and extent, and help with surgical planning. The criteria for diagnosing an ectopic pituitary adenoma depend on detailed histopathological examination. EPA management should be individualized. We present a case of a 71-year-old male who presented with a 9-month history of left nasal obstruction, purulent nasal discharge, and intermittent anterior epistaxis. The patient was being managed by his general practitioner for chronic rhinosinusitis but failure of his symptoms to resolve prompted a visit to the otorhinolaryngologist. The patient was diagnosed with a null-cell ectopic pituitary adenoma through histological analysis of a biopsy specimen that showed adenohypophyseal cells without cell-type-specific differentiation. The patient subsequently underwent an endoscopic endonasal excision and had an uneventful hospital stay.

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来源期刊
Case Reports in Otolaryngology
Case Reports in Otolaryngology OTORHINOLARYNGOLOGY-
自引率
0.00%
发文量
20
审稿时长
13 weeks
期刊最新文献
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