骨科植入物智能涂层的现状:综合综述

Q1 Engineering Smart Materials in Medicine Pub Date : 2023-01-01 DOI:10.1016/j.smaim.2023.06.005
Mansi Uday Joshi , Shruti Prakash Kulkarni , Mounika Choppadandi , M. Keerthana , Govinda Kapusetti
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引用次数: 3

摘要

生物材料在现代骨科中起着举足轻重的作用。骨科植入物存在大量功能问题。这些问题包括无菌性松动、缺乏骨整合、生物膜形成和感染。研究人员设计了几种表面修饰程序,包括对植入物表面进行涂层,以解决这些问题。植入物涂层充当植入物和周围生物成分之间的桥梁。其中一种创造性的方法是使用智能涂层对表面进行改性。智能涂层可以检测温度、pH值、光照等环境线索,进而对组织产生兼性反应。我们感兴趣的是一种特殊的刺激物及其在骨科植入物涂层中的特殊作用。一些涂层,称为双作用涂层,除了作为触发器的单个刺激之外,还允许利用一个或多个刺激。根据他们对刺激的反应,我们在当前的综述中重点介绍了最尖端的智能骨科植入物涂层。
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Current state of art smart coatings for orthopedic implants: A comprehensive review

Biomaterials play a pivotal role in modern orthopedics. There are a plethora of functional issues with orthopedic implants. These issues include things like aseptic loosening, lack of osseointegration, biofilm formation, and infections. Researchers have devised several surface modification procedures, including coating the implant surfaces, to address these problems. Implant coatings serve as a bridge between the implant and the surrounding bio components. One of the creative methods is to modify surfaces using smart coatings. Smart coatings can detect environmental cues like temperature, pH, light, and so on and in turn react facultatively to the tissues. A particular stimulus and its specific role in orthopedic implant coatings are of our interest. Some coatings, known as dual-acting coatings, allow for the utilization of one or more stimuli in addition to the individual stimulus as a trigger. Based on the stimuli that they react to, we have highlighted the most cutting-edge smart orthopedic implant coatings in the current review.

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来源期刊
Smart Materials in Medicine
Smart Materials in Medicine Engineering-Biomedical Engineering
CiteScore
14.00
自引率
0.00%
发文量
41
审稿时长
48 days
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