尼日利亚儿童发育迟缓和消瘦的时空映射:一个二元混合模型

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2023-10-06 DOI:10.1016/j.spasta.2023.100785
Ezra Gayawan , Osafu Augustine Egbon
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引用次数: 0

摘要

研究表明,发育迟缓和消瘦指标在儿童中密切相关,有可能同时影响他们的身体和认知发展。然而,识别具有不同发育迟缓和消瘦风险的儿童亚群对于有针对性的干预可能是有价值的。这项工作在贝叶斯框架内提出了一个双变量时空混合模型,以描述尼日利亚更广泛的五岁以下儿童群体中儿童亚群体的空间行为。该模型假设每个子种群遵循高斯分布,因此,通过概率地组合高斯子空间模型来对总体种群进行建模。推断基于马尔可夫链蒙特卡罗算法,该算法从联合后验分布中提取样本。该模型应用于尼日利亚人口与健康调查的四波数据。我们发现亚群中发育迟缓和消瘦之间存在显著的负相关,两种疾病的空间模式之间存在负空间相关性。研究结果表明,亚群之间的风险因素各不相同,发育迟缓和消瘦的可能性存在时空差异。研究结果强调,有必要制定一项全面的国家干预计划,以涉及社区和亚群体的方式关注高负担州。这些地图可以作为干预规划的宝贵工具。
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Spatio-temporal mapping of stunting and wasting in Nigerian children: A bivariate mixture modeling

Studies have shown that stunting and wasting indicators are strongly correlated among children, with the potential of concurrently affecting their physical and cognitive development. However, the identification of subpopulations of children with varying risks of stunting and wasting could be valuable for targeted intervention. This work proposed a bivariate spatio-temporal mixture model within a Bayesian framework to describe the spatial behavior of subpopulations of the children within the wider population of children under five years of age in Nigeria. The model assumes that each sub-population follows a Gaussian distribution, and therefore, the overall population is modeled by combining Gaussian sub-spatial models probabilistically. Inferences were based on the Markov chain Monte Carlo algorithm, that draw samples from the joint posterior distribution. The model was applied to data from four waves of the Nigerian Demographic and Health Survey. We identified a significant negative correlation between stunting and wasting among subpopulations with a negative spatial correlation between the spatial patterns of both illnesses. The findings demonstrate varying risk factors between the subpopulations with an evidence of spatio-temporal disparity in the likelihood of stunting and wasting. The findings underscore the need for a comprehensive national intervention program with attention given to high-burden states in a manner that involves communities and subpopulations. The maps could serve as a valuable tool for intervention planning.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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