第三个千年肝移植患者血流动力学监测

Giorgio Della Rocca , Alessandra Della Rocca
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引用次数: 2

摘要

在接受原位肝移植(OLTx)手术的患者中,最常用的术中血液动力学监测技术仍然是肺动脉导管(PAC)。经食道超声心动图(TEE)越来越受欢迎,因此今天的最新问题是:在临床实践中,是否应该限制PAC和/或容量监测与经肺热稀释和/或高级容量PAC的使用,仅针对一些高危患者?如果有必要,我们可以在接受OLTx手术的病情较轻的患者中使用TEE吗?我们可以将上述所有监控技术集成到一个日益模块化的逐步监控概念中。但在血液动力学不确定的情况下,经胸和/或经食管超声心动图评估是一个基石。超声心动图在OLTx中的应用越来越普遍,TEE在该患者群体中表现出了一些益处。在大出血的情况下,要实现和保持足够的组织灌注变得困难,这一事件很可能在OLTx期间发生,影响即时和晚期结果。所有临床医生都认为出血会干扰血液动力学监测的选择,反之亦然。一个合理的折衷方案是在扩大高危手术患者监测的需要和每个移植中心的血液制品平均消耗量之间找到平衡。这也符合文献中关于最大手术血液订购时间表(MSBOS)的内容。
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Hemodynamic monitoring in liver Transplantation patients in the third millennium

In patients undergoing orthotopic liver transplantation (OLTx) surgery, the intraoperative hemodynamic monitoring technique that is most utilized is still the pulmonary artery catheter (PAC). The popularity of transesophageal echocardiography (TEE) is increasing, so today's updated issue is the following: should the use of PAC and/or volumetric monitoring with transpulmonary thermodilution and/or advanced volumetric PAC be limited in clinical practice, only for some high risk patients? Could we use the TEE, if necessary, in less critical ill patients undergoing OLTx surgery?

We can integrate all of the aforementioned monitoring techniques in an increasing modular step wise monitoring concept. But in an uncertain hemodynamic situation, transthoracic and/or transoesophageal echocardiographic evaluation represents a cornerstone.

The use of echocardiography during OLTx is more and more common with several benefits demonstrated particularly by the TEE in this patient population.

To achieve and maintain adequate tissue perfusion becomes difficult in case of major bleeding, an event quite possible to occur during OLTx, affecting the immediate and the late outcome.

All the clinicians agree that bleeding interfere with the choice of hemodynamic monitoring and or vice versa.

A reasonable compromise is to find a balance between the need to extend monitoring in high-risk surgical patients and the average consumption of blood products that characterizes each individual transplant center. This is also in line with what is shown in literature in terms of Maximum Surgical Blood Ordering Schedule (MSBOS).

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