{"title":"具有非溶细胞治愈和Ornstein-Uhlenbeck过程的随机HIV模型动力学分析","authors":"Cheng Han, Yan Wang, Daqing Jiang","doi":"10.1016/j.chaos.2023.113930","DOIUrl":null,"url":null,"abstract":"<div><p>In this paper, we introduce an HIV infection model with virus-to-cell infection, cell-to-cell infection and non-cytolytic cure. Two mean-reverting Ornstein–Uhlenbeck processes are also taken into account in the model. Firstly, it is proved that the stochastic model has a unique positive global solution. The model is found to have at least one stationary distribution by constructing suitable Lyapunov functions if the critical condition <span><math><mrow><msubsup><mrow><mi>R</mi></mrow><mrow><mn>0</mn></mrow><mrow><mi>s</mi></mrow></msubsup><mo>></mo><mn>1</mn></mrow></math></span>. Then, the probability density function near the quasi-positive equilibrium is obtained by solving the corresponding Fokker–Planck equation. The spectral radius method is used to derive the virus extinction under a sufficient condition <span><math><mrow><msubsup><mrow><mi>R</mi></mrow><mrow><mn>0</mn></mrow><mrow><mi>e</mi></mrow></msubsup><mo><</mo><mn>1</mn></mrow></math></span>. Finally, some numerical simulations are carried out.</p></div>","PeriodicalId":9764,"journal":{"name":"Chaos Solitons & Fractals","volume":"175 ","pages":"Article 113930"},"PeriodicalIF":5.6000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Dynamics analysis of a stochastic HIV model with non-cytolytic cure and Ornstein–Uhlenbeck process\",\"authors\":\"Cheng Han, Yan Wang, Daqing Jiang\",\"doi\":\"10.1016/j.chaos.2023.113930\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>In this paper, we introduce an HIV infection model with virus-to-cell infection, cell-to-cell infection and non-cytolytic cure. Two mean-reverting Ornstein–Uhlenbeck processes are also taken into account in the model. Firstly, it is proved that the stochastic model has a unique positive global solution. The model is found to have at least one stationary distribution by constructing suitable Lyapunov functions if the critical condition <span><math><mrow><msubsup><mrow><mi>R</mi></mrow><mrow><mn>0</mn></mrow><mrow><mi>s</mi></mrow></msubsup><mo>></mo><mn>1</mn></mrow></math></span>. Then, the probability density function near the quasi-positive equilibrium is obtained by solving the corresponding Fokker–Planck equation. The spectral radius method is used to derive the virus extinction under a sufficient condition <span><math><mrow><msubsup><mrow><mi>R</mi></mrow><mrow><mn>0</mn></mrow><mrow><mi>e</mi></mrow></msubsup><mo><</mo><mn>1</mn></mrow></math></span>. Finally, some numerical simulations are carried out.</p></div>\",\"PeriodicalId\":9764,\"journal\":{\"name\":\"Chaos Solitons & Fractals\",\"volume\":\"175 \",\"pages\":\"Article 113930\"},\"PeriodicalIF\":5.6000,\"publicationDate\":\"2023-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chaos Solitons & Fractals\",\"FirstCategoryId\":\"100\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0960077923008317\",\"RegionNum\":1,\"RegionCategory\":\"数学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/8/21 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"MATHEMATICS, INTERDISCIPLINARY APPLICATIONS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chaos Solitons & Fractals","FirstCategoryId":"100","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0960077923008317","RegionNum":1,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/8/21 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"MATHEMATICS, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
Dynamics analysis of a stochastic HIV model with non-cytolytic cure and Ornstein–Uhlenbeck process
In this paper, we introduce an HIV infection model with virus-to-cell infection, cell-to-cell infection and non-cytolytic cure. Two mean-reverting Ornstein–Uhlenbeck processes are also taken into account in the model. Firstly, it is proved that the stochastic model has a unique positive global solution. The model is found to have at least one stationary distribution by constructing suitable Lyapunov functions if the critical condition . Then, the probability density function near the quasi-positive equilibrium is obtained by solving the corresponding Fokker–Planck equation. The spectral radius method is used to derive the virus extinction under a sufficient condition . Finally, some numerical simulations are carried out.
期刊介绍:
Chaos, Solitons & Fractals strives to establish itself as a premier journal in the interdisciplinary realm of Nonlinear Science, Non-equilibrium, and Complex Phenomena. It welcomes submissions covering a broad spectrum of topics within this field, including dynamics, non-equilibrium processes in physics, chemistry, and geophysics, complex matter and networks, mathematical models, computational biology, applications to quantum and mesoscopic phenomena, fluctuations and random processes, self-organization, and social phenomena.