{"title":"眼眶脑膜瘤:我们对它们了解多少?","authors":"Neil Saldías Valenzuela","doi":"10.1016/j.rmclc.2023.08.002","DOIUrl":null,"url":null,"abstract":"<div><p>Among the tumor pathologies that can affect the orbit, meningiomas, be they primary or secondary, stand out. These tumors grow slowly, in the long term eventually compressing the optic nerve and other structures such as extra-ocular muscles and the eyeball. This translates into exophthalmos and chronic vision loss that can lead to blindness in the affected eye. The adequate clinical interpretation of this medical condition, associated with the use of neuroimaging, mainly computed tomography and magnetic resonance imaging, allow us to make a timely diagnosis. Treatment is primarily based on fractionated stereotactic radiotherapy when the tumor is advancing and the focus is on vision preservation. Surgery is indicated when vision has already been significantly lost or there is a threat of invasion of the optic chiasm. Chemotherapy treatment options are still under study. The vital prognosis of this pathology is good, but functionally it can leave significant sequelae depending on the behavior of the tumor, as well as how early we make its diagnosis.</p><p>The objective of this article is to comment on the current state of what is known about orbital meningiomas, their diagnosis and existing therapeutic alternatives.</p></div>","PeriodicalId":31544,"journal":{"name":"Revista Medica Clinica Las Condes","volume":"34 5","pages":"Pages 322-326"},"PeriodicalIF":0.2000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Meningiomas Orbitarios: ¿que sabemos de ellos?\",\"authors\":\"Neil Saldías Valenzuela\",\"doi\":\"10.1016/j.rmclc.2023.08.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Among the tumor pathologies that can affect the orbit, meningiomas, be they primary or secondary, stand out. These tumors grow slowly, in the long term eventually compressing the optic nerve and other structures such as extra-ocular muscles and the eyeball. This translates into exophthalmos and chronic vision loss that can lead to blindness in the affected eye. The adequate clinical interpretation of this medical condition, associated with the use of neuroimaging, mainly computed tomography and magnetic resonance imaging, allow us to make a timely diagnosis. Treatment is primarily based on fractionated stereotactic radiotherapy when the tumor is advancing and the focus is on vision preservation. Surgery is indicated when vision has already been significantly lost or there is a threat of invasion of the optic chiasm. Chemotherapy treatment options are still under study. The vital prognosis of this pathology is good, but functionally it can leave significant sequelae depending on the behavior of the tumor, as well as how early we make its diagnosis.</p><p>The objective of this article is to comment on the current state of what is known about orbital meningiomas, their diagnosis and existing therapeutic alternatives.</p></div>\",\"PeriodicalId\":31544,\"journal\":{\"name\":\"Revista Medica Clinica Las Condes\",\"volume\":\"34 5\",\"pages\":\"Pages 322-326\"},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2023-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Medica Clinica Las Condes\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0716864023000706\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Medica Clinica Las Condes","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0716864023000706","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Among the tumor pathologies that can affect the orbit, meningiomas, be they primary or secondary, stand out. These tumors grow slowly, in the long term eventually compressing the optic nerve and other structures such as extra-ocular muscles and the eyeball. This translates into exophthalmos and chronic vision loss that can lead to blindness in the affected eye. The adequate clinical interpretation of this medical condition, associated with the use of neuroimaging, mainly computed tomography and magnetic resonance imaging, allow us to make a timely diagnosis. Treatment is primarily based on fractionated stereotactic radiotherapy when the tumor is advancing and the focus is on vision preservation. Surgery is indicated when vision has already been significantly lost or there is a threat of invasion of the optic chiasm. Chemotherapy treatment options are still under study. The vital prognosis of this pathology is good, but functionally it can leave significant sequelae depending on the behavior of the tumor, as well as how early we make its diagnosis.
The objective of this article is to comment on the current state of what is known about orbital meningiomas, their diagnosis and existing therapeutic alternatives.