每天快走11分钟可降低早逝风险

Iskandar Idris
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引用次数: 0

摘要

目前的指导方针建议至少150 每周中等强度活动的分钟数(如快走、骑自行车或打网球)或75 每周剧烈活动的分钟数,分布在4-5 以降低心血管疾病(CVD)的风险。尽管有这一适度的建议,但由于时间限制,普通人群对这一活动水平的接受率仍然很低。剑桥大学MRC流行病学部门的研究人员在《英国运动医学杂志》上发表了一项新的研究,旨在探索对几种慢性病和过早死亡产生有益影响所需的体育活动量。其中一个主要目的是了解体力活动水平与过早死亡和慢性疾病结果之间的剂量-反应关系。为此,研究人员对来自94个大型研究队列的196篇同行评审文章进行了系统综述和荟萃分析,涵盖了3000多万参与者。根据研究人员的说法,这使他们能够对体力活动水平与心脏病、癌症和早逝风险之间的关系进行迄今为止最大的分析。根据他们的分析,他们得出结论,除了与工作相关的体育活动外,三分之二的人报告的活动水平低于150 每周至少进行一次中等强度的活动,不到十分之一的人管理了300多次 每周分钟。总体而言,较高的体育活动水平与所有结果的风险较低有关。与不活跃的人相比,达到150 中等强度活动min的全因死亡率降低31%,心血管疾病死亡率降低29%,癌症死亡率降低15%。如果所有个人累计至少150 每周至少一分钟,那么全因、CVD相关和癌症相关死亡的比例分别为15.7%、12.3%和7.1%,“可能已经避免”。研究人员还计算出,如果研究中的每个人都做了至少150次 每周分钟的中等强度活动、约六分之一(15.7%)的过早死亡、九分之一(10.9%)的心血管疾病病例和二十分之一(5.2%)的癌症病例都可以预防。他们还发现“超过”150 每周分钟的中等强度活动,在降低疾病或早逝风险方面的额外益处是“微不足道的”。重要的是,即使将体育活动量减少一半也会带来显著的好处。累计75 每周分钟的中等强度活动使早期死亡的风险降低23%。如果每个人都能做到至少75 每周分钟的中等强度体力活动、约十分之一(10%)的过早死亡、1/20(5%)的心血管疾病病例和近1/30(3%)的癌症病例将得到预防。每周75分钟的适度活动也足以降低17%的心血管疾病风险和7%的癌症风险。因此,研究表明,进行一定程度的活动总比不进行要好。对于那些难以达到建议的150分的人来说尤其如此 每周至少进行中等强度的体育活动。因此,’11 每天分钟--75 作者表示,每周至少进行一次中等强度的体育活动,如快走,就足以降低患心脏病、中风和多种癌症等疾病的风险。
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Eleven-minutes of brisk walk a day shown to reduce risk of early death

Current guideline recommends at least a 150 min of moderate intensity activity a week (e.g., brisk walking, cycling or playing tennis) or 75 min of vigorous intensity activity a week, spread over 4–5 days a week to reduce risks of cardiovascular disease (CVD). Despite this modest recommendation, uptake for this level of activity remains low in the general population due to time commitments. A new study, published in the British Journal of Sports Medicine conducted by researchers from the MRC Epidemiology Unit at the University of Cambridge has set out to explore the amount of physical activity necessary to have a beneficial impact on several chronic diseases and premature death. One of the main aim is to understand the shape of the dose–response association between levels of physical activity with premature death and chronic disease outcomes.

To do this, researchers performed a systematic review and meta-analysis of 196 peer-reviewed articles, covering more than 30 million participants, from 94 large study cohorts. This, according to the investigators enabled them to produce the largest analysis to date of the association between physical activity levels and risk of heart disease, cancer, and early death.

From their analyses, they concluded that, apart from work-related physical activity, 2 in 3 people reported activity levels below 150 min per week of moderate-intensity activity, and fewer than 1 in 10 managed more than 300 min per week. Overall, higher activity levels of physical activities were associated with lower risks of all outcomes. Compared with inactive individuals, adults who achieved the 150 min of moderate-intensity activity had a 31% lower risk of all-cause mortality, a 29% lower risk of CVD mortality, and a 15% lower risk of cancer mortality. If all individuals accumulated at least 150 min a week, then 15.7%, 12.3%, and 7.1% of all-cause, CVD-related, and cancer-related deaths, respectively, would ‘potentially have been averted’. The researchers also calculated that if everyone in the studies had done the equivalent of at least 150 min per week of moderate-intensity activity, around 1 in 6 (15.7%) premature deaths, 1 in 9 (10.9%) cases of CVD, and 1 in 20 (5.2%) cases of cancer, would have been prevented.

They also found that ‘beyond’ 150 min per week of moderate-intensity activity, the additional benefits in terms of reduced risk of disease or early death were ‘marginal’. Importantly, even reducing the amount of physical activity by half also came with significant benefits. Accumulating 75 min per week of moderate-intensity activity brought with it a 23% lower risk of early death. If everyone managed at least 75 min per week of moderate-intensity physical activity, around 1 in 10 (10%) premature deaths, 1 in 20 (5%) cases of CVD, and nearly 1 in 30 (3%) cases of cancer, would be prevented. Seventy-five minutes per week of moderate activity was also enough to reduce the risk of developing CVD by 17% and cancer by 7%.

The study therefore suggests that doing some level of activity is better than doing none. This is particularly so for individuals who struggles to do the recommended 150 min of moderate-intensity physical activity a week. Thus, ‘11 min a day—75 min a week—of moderate-intensity physical activity—such as a brisk walk—would be sufficient to lower the risk of diseases such as heart disease, stroke, and a number of cancers’, according to the authors.

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