分娩硬膜外镇痛过程中非故意硬膜穿刺的并发症:一项10年回顾性观察研究。

S Poma, M C Bonomo, G Gazzaniga, M Pizzulli, A De Silvestri, C Baldi, F Broglia, M Ciceri, M Fuardo, F Morgante, S Pellicori, E M Roldi, M P Delmonte, F Mojoli, A Locatelli
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引用次数: 0

摘要

引言:意外硬膜外穿刺(UDP)发生在0.5-1.5%的分娩硬膜外镇痛病例中。迄今为止,对UDP相关并发症的证据知之甚少。这项工作旨在评估患有UDP的产妇的产时和产后并发症的发生率。方法:这是一项为期10年的回顾性观察研究,研究对象是我们中心收治的患有UDP的孕妇。数据收集收集了分娩和产后UDP相关并发症。所有显示UDP的女性都接受了药物治疗和卧床休息。在这一人群中没有使用硬膜外血液贴片(EBP)。一旦没有症状,病人就出院了。结果:7718例神经轴镇痛病例中,发生UDP 97例(1.25%)。分娩过程中,并发症出现在一小部分镇痛程序中,包括全脊麻(1.0%)、延长运动阻滞(3%)、低血压(4.1%)、胎心率异常(2%)、镇痛不足(14.4%),以及神经轴麻醉失败后的全身麻醉(33.3%的紧急剖腹产)。在产后期间,53.6%的产妇出现硬膜后穿刺头痛,13.4%的产妇出现神经症状,14.4%的产妇需要进行神经咨询和神经影像学检查。没有患者出现硬膜下血肿或脑静脉窦血栓形成;一名妇女出现与子痫相关的后部可逆性脑病综合征。总体而言,82.5%的女性经历了住院时间的延长。结论:分娩过程中发生主要并发症的患者比例很小。然而,由于它们代表了高风险的孕产妇和新生儿健康事件,一名专职麻醉师和一支训练有素的产科团队至关重要。产后未出现重大神经系统并发症,也未进行EBP。尽管如此,所有UDP患者都受到了仔细的监测和治疗,直到出院前完全康复,从而延长了住院时间。
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Complications of unintentional dural puncture during labour epidural analgesia: a 10-year retrospective observational study.

Introduction: Unintentional dural puncture (UDP) occurs in 0.5-1.5% of labour epidural analgesia cases. To date, little is known about evidence of UDP-related complications. This work aimed to assess the incidence of intrapartum and postpartum complications in parturients who experienced UDP.

Methods: This is a 10-year retrospective observational study on parturients admitted to our centre who presented UDP. Data collection gathered UDP-related complications during labour and postpartum. All women who displayed UDP received medical therapy and bed rest. An epidural blood patch (EBP) was not used in this population. Once asymptomatic, patients were discharged from the hospital.

Results: Out of 7718 neuraxial analgesia cases, 97 cases of UDP occurred (1.25%). During labour, complications appeared in a small percentage of analgesia procedures performed, including total spinal anaesthesia (1.0%), extended motor block (3%), hypotension (4.1%), abnormal foetal heart rate (2%), inadequate analgesia (14.4%), and general anaesthesia following neuraxial anaesthesia failure (33.3% of emergency caesarean sections). During the postpartum period, 53.6% of parturients exhibited a postdural puncture headache, 13.4% showed neurological symptoms, and 14.4% required neurological consultation and neuroimaging. No patient developed subdural hematoma or cerebral venous sinus thrombosis; one woman presented posterior reversible encephalopathy syndrome associated with eclampsia. Overall, 82.5% of women experienced an extension of hospital stay.

Conclusion: Major complications occurred in a small percentage of patients during labour. However, since they represent high-risk maternal and neonatal health events, a dedicated anaesthesiologist and a trained obstetric team are essential. No major neurological complications were registered postpartum, and EBP was not performed. Nevertheless, all patients with UDP were carefully monitored and treated until complete recovery before discharge, leading to an extension of their hospitalization.

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