Aleksandar Savić;Fabian Freiberger;Ralf Pörtner;Arne F. Jacob
{"title":"高达40GHz的平面微芯片传感器对CHO和HepG2单细胞的表征","authors":"Aleksandar Savić;Fabian Freiberger;Ralf Pörtner;Arne F. Jacob","doi":"10.1109/JERM.2023.3257480","DOIUrl":null,"url":null,"abstract":"The article deals with broadband microwave measurements performed on single dead and living biological cells from CHO and HepG2 cell lines. It reports results obtained with coplanar waveguide reflection and transmission type sensors, respectively. A straight-forward single liquid calibration procedure allows to extract the complex cell permittivity and compare it to that of the surrounding medium. The contrast is analyzed through \n<inline-formula><tex-math>$p$</tex-math></inline-formula>\n-value tests and in terms of the usual Cole-Cole parameters. The results demonstrate the distinguishability of the cell lines based on the permittivity.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":"7 3","pages":"236-244"},"PeriodicalIF":3.0000,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"CHO and HepG2 Single-Cell Characterization With Planar Microchip Sensors up to 40 GHz\",\"authors\":\"Aleksandar Savić;Fabian Freiberger;Ralf Pörtner;Arne F. Jacob\",\"doi\":\"10.1109/JERM.2023.3257480\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The article deals with broadband microwave measurements performed on single dead and living biological cells from CHO and HepG2 cell lines. It reports results obtained with coplanar waveguide reflection and transmission type sensors, respectively. A straight-forward single liquid calibration procedure allows to extract the complex cell permittivity and compare it to that of the surrounding medium. The contrast is analyzed through \\n<inline-formula><tex-math>$p$</tex-math></inline-formula>\\n-value tests and in terms of the usual Cole-Cole parameters. The results demonstrate the distinguishability of the cell lines based on the permittivity.\",\"PeriodicalId\":29955,\"journal\":{\"name\":\"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology\",\"volume\":\"7 3\",\"pages\":\"236-244\"},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2023-03-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://ieeexplore.ieee.org/document/10079914/\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENGINEERING, ELECTRICAL & ELECTRONIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","FirstCategoryId":"1085","ListUrlMain":"https://ieeexplore.ieee.org/document/10079914/","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}
CHO and HepG2 Single-Cell Characterization With Planar Microchip Sensors up to 40 GHz
The article deals with broadband microwave measurements performed on single dead and living biological cells from CHO and HepG2 cell lines. It reports results obtained with coplanar waveguide reflection and transmission type sensors, respectively. A straight-forward single liquid calibration procedure allows to extract the complex cell permittivity and compare it to that of the surrounding medium. The contrast is analyzed through
$p$
-value tests and in terms of the usual Cole-Cole parameters. The results demonstrate the distinguishability of the cell lines based on the permittivity.
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