远端血运重建与糖尿病足

G. Sutton, J. Wolfe
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摘要

在英国,患有足部疾病的糖尿病患者比患有其他任何糖尿病并发症的糖尿病患者占用更多的医院床位。这些足部问题是由神经病变和缺血共同引起的,它们可能共存,并容易导致感染和随后的组织坏死。如果没有熟练的、多学科的管理,这些足部问题很容易发展到截肢。这个问题的严重程度不容低估。被送到假肢装配中心的截肢者中有20%患有糖尿病,三分之一的血管截肢是在糖尿病患者身上进行的。在这些失去一条腿的糖尿病患者中,50%的人将在五年内失去另一条腿。几乎可以肯定,这些数字低估了糖尿病截肢的比例,因为它们只涉及在假肢装配中心看到的患者:糖尿病患者通常有其他主要系统疾病,例如心脏或视力问题,这可能妨碍假肢装配。怎样才能避免肢体丧失呢?直到最近,糖尿病的缺血性并发症被认为是由于所谓的“小血管疾病”,因此不适合任何形式的手术干预。事实上,多年来,人们一直认为,如果腘窝脉搏可触到,就不可能进行任何形式的血管重建。
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Distal revascularisation and the diabetic foot
The scale of the problem More hospital beds in the United Kingdom are occupied by diabetic patients with foot problems than by patients with diabetes with any of the other complications of diabetes. These foot problems are caused by a combination of neuropathy and ischaemia, which may co-exist and together predispose to development of infection and subsequent tissue necrosis. Without skilled, multi-disciplinary, management these foot problems can easily progress to amputation. The scale of the problem cannot be understated. Twenty per cent of amputees referred to limb fitting centres have diabetes, and a third of all vascular amputations are carried out in people with diabetes. Fifty per cent of these patients with diabetes who lose a leg will lose the other one within five years. These figures are almost certainly an underestimate of the proportion of diabetic amputations as they only refer to patients seen in limb fitting centres: people with diabetes often have other major system disorders including, for example, cardiac or visual problems which may preclude limb fitting. How can this limb loss be averted? Until recently, the ischaemic complications of diabetes were said to be due to so-called 'small vessel disease' and therefore were not amenable to any form of surgical intervention. Indeed, for many years it was taught that if the popliteal pulse was palpable, no form of vascular reconstruction was possible.
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