应用GRADE方法对髋关节置换术前后患者功能锻炼的临床护理路径进行系统评价

Lin Yang , Xin-Man Wang , Xiao-Lin Zuo , Shang-Qun Gong , Fan-Jie Meng
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引用次数: 3

摘要

目的评价临床护理路径在髋关节置换术患者术前术后功能锻炼中的应用效果。方法检索中国知网(CNKI)、万方数据、中国科技期刊数据库(VIP)、PubMed、Web of science、EMBASE、CBM、Cochrane Library(2015-5),检索2015年6月- 2010年1月髋关节置换术患者术前术后功能锻炼临床护理路径的随机对照试验(RCTs)。还检索了文献中包含的参考文献。为满足文献标准,2名审稿人根据纳入标准独立选择和提取资料,并评估偏倚风险。meta分析采用RevMan 5.3软件。使用grade profiler3.6软件评估证据质量,这是推荐的评分级别。结果共纳入15项随机对照试验,1248例患者。meta分析显示,临床护理路径组患者髋关节功能Harris评分[SMD = 3.35, 95%CI (2.53, 4.16), P <[0.00001]和血栓栓塞发生率[RR = 0.28, 95%CI (0.15, 0.53), P <0.0001)、肺部感染(RR = 0.33, 95%可信区间(0.14,0.82),P = 0.02),尿潴留(RR = 0.22, 95%可信区间(0.09,0.52),P = 0.0005),便秘(RR = 0.20, 95%可信区间(0.10,0.40),P & lt;0.00001],患者护理满意度[RR = 1.26, 95%CI (1.17, 1.36), P <0.00001]缩短住院时间[SMD = - 1.91, 95%CI (- 2.39, - 1.43), P <0.0001]均显著优于对照组。但在减少关节脱位[RR = 0.25, 95%CI (0.05, 1.15), P = 0.08]、压疮[RR = 0.25, 95%CI (0.03, 2.19), P = 0.21]、并发症发生率[RR = 0.42, 95%CI (0.15, 1.12), P = 0.08]方面,两组差异无统计学意义。平均住院时间的漏斗图分析显示,文献中可能存在一定的发表偏倚。GRADE评价结果显示Harris评分髋关节功能水平为中等,血栓发生率、尿潴留发生率和患者对护理的满意度较低,其余分析因素均很低。结论临床护理路径应用于髋关节置换术患者术前术后功能锻炼的效果明显优于常规护理。但受研究成果评价等级和研究的规范性、统一性等因素的制约。上述研究的结果需要更多高质量的rct来验证。
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Systematic evaluation of the clinical nursing pathway with the GRADE approach applied to functional exercise in patients with hip replacements before and after surgery

Objective

To evaluate the effect of the clinical nursing pathway applied to functional exercise in patients with hip replacements before and after the operation.

Methods

The China National Knowledge Infrastructure (CNKI), WanFang Data, Chinese science and technology journal database (VIP), PubMed, Web of Science, EMBASE, CBM and the Cochrane Library (2015-5) were searched for randomized controlled trials (RCTs) on clinical nursing pathways for functional exercise in patients with hip replacements before and after surgery from June 2015 to January 2010. The references included in the literature were also retrieved. To meet the literature standard, 2 reviewers independently selected and extracted data according to the inclusion criteria and assessed the risks of bias. RevMan 5.3 software was used in this meta-analysis. The quality of evidence was evaluated using grade profiler3.6 software, the level recommended for grading.

Results

A total of 15 RCTs and 1248 patients were included. The meta-analysis showed that, in the clinical nursing path group, the Harris score of hip function [SMD = 3.35, 95%CI (2.53, 4.16), P < 0.00001] and incidence of thrombosis embolism [RR = 0.28, 95%CI (0.15, 0.53), P < 0.0001], pulmonary infection [RR = 0.33, 95%CI (0.14, 0.82), P = 0.02], urinary retention [RR = 0.22, 95%CI (0.09, 0.52), P = 0.0005], constipation [RR = 0.20, 95%CI (0.10, 0.40), P < 0.00001], patients' satisfaction for nursing care [RR = 1.26, 95%CI (1.17, 1.36), P < 0.00001] and shortened hospitalization times [SMD = −1.91, 95%CI (−2.39, −1.43), P < 0.0001]were statistically significantly better than those in the control group. However, in reducing joint dislocations [RR = 0.25, 95%CI (0.05, 1.15), P = 0.08], pressure ulcers [RR = 0.25, 95%CI (0.03, 2.19), P = 0.21], and incidence of complications [RR = 0.42, 95%CI (0.15, 1.12), P = 0.08], there was no statistically significant difference between the two groups. Funnel plot analysis of the average length of stay showed that there might be some publication bias in the literature. The GRADE evaluation results showed that the level of Harris scores for hip function was moderate and the incidence of thrombosis, urinary retention and satisfaction of patients regarding nursing were low, and the rest of the factors analyzed were very low.

Conclusions

The effect of the clinical nursing pathway applied to functional exercises in patients with hip replacements before and after surgery was significantly better than that of routine nursing. However, it was restricted by the evaluation grade of the research results and the standardization and uniformity of the research. The results of the above study need to be verified by more high-quality RCTs.

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