丝状真菌的基因组学——从面包师酵母的阴影中移动

Simon J. Foster , Brendon J. Monahan , Rosie E. Bradshaw
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引用次数: 7

摘要

真菌现在已经真正进入了基因组时代。我们目前已知18种真菌的完整DNA序列,更多的真菌基因组测序项目正在进行中。虽然酵母菌主导了早期的基因组年,最近有丝状真菌基因组计划急剧增加。这种丰富的遗传信息对全世界真菌学家的意义是巨大的。在这篇综述中,我们总结了真菌基因组计划的背景,重点是丝状真菌。我们讨论了确定基因功能和比较不同物种基因组的努力。由于这是一个快速发展的领域,因此列出了一些有用的网站,使读者能够跟上最新的发展。
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Genomics of the filamentous fungi – moving from the shadow of the bakers yeast

Fungi have now well and truly entered the genomic age. We currently know the complete DNA sequence for 18 fungal species and many more fungal genome sequencing projects are in progress. Whilst yeasts dominated the early genomic years, recently there has been a dramatic increase in filamentous fungal genome projects. The implications of this wealth of genetic information for mycologists worldwide is immense. In this review we summarise the background to fungal genome projects with an emphasis on the filamentous fungi. We discuss efforts to determine gene function and to compare genomes from different species. Since this is such a fast-moving field, useful web sites are listed that will enable the reader to keep up to date with developments.

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