尼日利亚无症状儿童的疟疾缺铁性贫血

Zaccheaus Awortu. Jeremiah, Uko Ek, F. Buseri, T. A. Jeremiah
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引用次数: 5

摘要

目的。在我们地区普遍存在亚临床(无症状)疟疾。疟疾对机体铁状态的影响尚不完全清楚。本研究的目的是调查疟疾缺铁性贫血的患病率以及无症状疟疾对铁状态指标的影响。横断面前瞻性研究。对240名1-8岁男女儿童的血红蛋白浓度、白细胞(WBC)计数、疟疾寄生虫、血清铁、总铁结合能力(TIBC)、血清铁蛋白和转铁蛋白饱和度百分比进行了评估。使用标准血液学、比色法和酶联免疫吸附测定程序对变量进行估计。240例儿童中66例(27.5%)感染恶性疟原虫。缺铁性贫血(定义为血红蛋白<11 g dl - 1,血清铁蛋白<12 ng ml - 1,转铁蛋白饱和度<16%)的总体患病率是…
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Malarial iron-deficiency anaemia among asymptomatic Nigerian children
Purpose. There is widespread subclinical (asymptomatic) malaria in our locality. The effects exerted by malaria on the body iron status remain incompletely understood. The aim of this study was to investigate the prevalence of malarial iron‐deficiency anaemia and the effect of asymptomatic malaria on iron status indicators.Design. A cross‐sectional prospective study.Methods. Seven parameters, haemoglobin concentration, white blood cell (WBC) count, malaria parasite, serum iron, total iron binding capacity (TIBC), serum ferritin, and percentage transferrin saturation, were evaluated among 240 children of both genders, aged 1–8 years. Estimation of the variables was carried out using standard haematological, colorimetric and enzyme‐linked immunosorbent assay procedures.Results. Of the 240 children surveyed, 66 (27.5%) were parasitized with Plasmodium falciparum. The overall prevalence of iron‐deficiency anaemia (defined as haemoglobin <11 g dl−1, serum ferritin <12 ng ml−1 and transferrin saturation <16%) i...
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