{"title":"产自博茨瓦纳的松果木的抗氧化和抗糖尿病潜能","authors":"T. Kwape, R. Majinda, P. Chaturvedi","doi":"10.1080/23312025.2016.1275403","DOIUrl":null,"url":null,"abstract":"Abstract The total phenol content, antioxidant and antidiabetic activity of Myrothamnus flabellifolius (MF) were investigated. The study revealed 70% ethanol/water (EW70), 70% methanol/water (MW70) and methanol (Me) extracts to contain the highest phenol content, 350 mg GAE/g, 300 mg GAE/g and 250 mg GAE/g, respectively (GAE/g—Gallic Acid Equivalent per gram). MW70 exhibited the highest radical [diphenyl picryl hydrazine (DPPH) and 2, 2-Azobis-3-ethyl benzthiazoline-6-sulphonic acid (ABTS+)] scavenging power. About 70% ethanol/water exhibited the highest reducing power, hydrogen peroxide and nitric oxide scavenging activities. The results of antidiabetic activity showed EW70 to possess the highest α-amylase inhibitory effect. The α-glucosidase activity was inhibited by EW70, n-Butanol fraction and ethyl acetate fraction, respectively. The results of the study suggest MF as a beneficial natural medicine.","PeriodicalId":10412,"journal":{"name":"Cogent Biology","volume":"2 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2016-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/23312025.2016.1275403","citationCount":"9","resultStr":"{\"title\":\"Antioxidant and antidiabetic potential of Myrothamnus flabellifolius found in Botswana\",\"authors\":\"T. Kwape, R. Majinda, P. Chaturvedi\",\"doi\":\"10.1080/23312025.2016.1275403\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract The total phenol content, antioxidant and antidiabetic activity of Myrothamnus flabellifolius (MF) were investigated. The study revealed 70% ethanol/water (EW70), 70% methanol/water (MW70) and methanol (Me) extracts to contain the highest phenol content, 350 mg GAE/g, 300 mg GAE/g and 250 mg GAE/g, respectively (GAE/g—Gallic Acid Equivalent per gram). MW70 exhibited the highest radical [diphenyl picryl hydrazine (DPPH) and 2, 2-Azobis-3-ethyl benzthiazoline-6-sulphonic acid (ABTS+)] scavenging power. About 70% ethanol/water exhibited the highest reducing power, hydrogen peroxide and nitric oxide scavenging activities. The results of antidiabetic activity showed EW70 to possess the highest α-amylase inhibitory effect. The α-glucosidase activity was inhibited by EW70, n-Butanol fraction and ethyl acetate fraction, respectively. The results of the study suggest MF as a beneficial natural medicine.\",\"PeriodicalId\":10412,\"journal\":{\"name\":\"Cogent Biology\",\"volume\":\"2 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1080/23312025.2016.1275403\",\"citationCount\":\"9\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cogent Biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/23312025.2016.1275403\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cogent Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/23312025.2016.1275403","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Antioxidant and antidiabetic potential of Myrothamnus flabellifolius found in Botswana
Abstract The total phenol content, antioxidant and antidiabetic activity of Myrothamnus flabellifolius (MF) were investigated. The study revealed 70% ethanol/water (EW70), 70% methanol/water (MW70) and methanol (Me) extracts to contain the highest phenol content, 350 mg GAE/g, 300 mg GAE/g and 250 mg GAE/g, respectively (GAE/g—Gallic Acid Equivalent per gram). MW70 exhibited the highest radical [diphenyl picryl hydrazine (DPPH) and 2, 2-Azobis-3-ethyl benzthiazoline-6-sulphonic acid (ABTS+)] scavenging power. About 70% ethanol/water exhibited the highest reducing power, hydrogen peroxide and nitric oxide scavenging activities. The results of antidiabetic activity showed EW70 to possess the highest α-amylase inhibitory effect. The α-glucosidase activity was inhibited by EW70, n-Butanol fraction and ethyl acetate fraction, respectively. The results of the study suggest MF as a beneficial natural medicine.
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