春季角结膜炎的治疗:在不断变化的治疗环境中导航。

IF 5.1 2区 医学 Q1 OPHTHALMOLOGY Survey of ophthalmology Pub Date : 2024-03-01 DOI:10.1016/j.survophthal.2023.10.008
Asim Ali MD , Leonard Bielory MD , Stephanie Dotchin MD, FRCSC , Patrick Hamel MD, FRCSC , Yi Ning J. Strube MD, MS, FRCSC , Euna B. Koo MD
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引用次数: 0

摘要

春季角结膜炎(VKC)是一种慢性、进行性和潜在的视力威胁型眼部炎症性疾病,主要影响儿童和年轻人。流行率因地区而异,从
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Management of vernal keratoconjunctivitis: Navigating a changing treatment landscape

Vernal keratoconjunctivitis (VKC) is a chronic, progressive, and potentially sight-threatening form of ocular inflammatory disease that primarily affects children and young adults. Prevalence varies by region, ranging from <2 per 10,000 in the United States to as high as 1,100 per 10,000 in parts of Africa. The rarity of VKC in developed countries can make differential diagnosis challenging, and treatment is often delayed until the disease is advanced, and symptoms are significantly impacting patients’ quality of life. Although once viewed primarily as an immunoglobulin E-mediated condition, approximately 50% of patients with VKC do not exhibit allergic sensitization. It is now recognized that the immunopathology of VKC involves multiple inflammatory pathways that lead to the signs, symptoms, and conjunctival eosinophilic and fibroproliferative lesions that are a hallmark of the disease. We examine the evolution of our understanding of the immunopathology of VKC, the expanding VKC treatment armamentarium, the clinical implications of emerging treatment approaches, and future directions for VKC research and practice.

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来源期刊
Survey of ophthalmology
Survey of ophthalmology 医学-眼科学
CiteScore
10.30
自引率
2.00%
发文量
138
审稿时长
14.8 weeks
期刊介绍: Survey of Ophthalmology is a clinically oriented review journal designed to keep ophthalmologists up to date. Comprehensive major review articles, written by experts and stringently refereed, integrate the literature on subjects selected for their clinical importance. Survey also includes feature articles, section reviews, book reviews, and abstracts.
期刊最新文献
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