US Policy Proposals for Gain-of-Function Research Raise Global Questions

Officials seem poised to accept the updated broad framework for assessing gain-of function (GoF) research proposals that the National Science Advisory Board for Biosecurity (NSABB) developed last year, making it the basis for federal policy. As part of a painstaking vetting of those proposals, NSABB members presented their draft guidance publicly under the auspices of the National Academy of Sciences (NAS) in Washington, D.C., in March, asking for feedback from scientific and science policy experts.