树突和共形对称的锥形索方程的解析解

J. M. Romero, C. Trenado
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引用次数: 0

摘要

在树突结构和生物物理特性的详细表征方面取得的进展强调了为具有圆形截面和变直径的更现实的树突模型寻找解析解的重要性。在这方面,我们采用对称方法和无源电缆理论来推导渐尖枝晶族中的电传播的广义解析解。特别地,我们研究了这种锥形几何形状对得到的电压的影响。利用推导出的解析解进行的仿真结果表明,对于锥度剖面亚族,神经积分优于圆柱体给出的典型剖面。
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Analytical Solution of a Tapering Cable Equation for Dendrites and Conformal Symmetry
Progress towards detailed characterization of structural and biophysical properties of dendrites emphasizes the importance of finding analytical solutions for more realistic dendrite models with circular cross-section and varying diameter. In this regard, we employ symmetry methods and the passive cable theory to deduce a generalized analytical solution for electric propagation in a family of tapering dendrites. In particular, we study the effect of such tapering geometries on the obtained electric voltage. Simulations using the deduced analytical solution indicate that for a subfamily of tapering profiles neural integration is better than in the stereotypical profile given by a cylinder.
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