生物序列的快速位并行多模式字符串匹配算法

Q2 Medicine In Silico Biology Pub Date : 2010-02-15 DOI:10.1145/1722024.1722077
R. Prasad, S. Agarwal, I. Yadav, Bharat Singh
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引用次数: 4

摘要

搜索模式P[0…]出现的问题m-1]在文本T[0…]n-1>, m≤n,其中P和T的符号取自大小为Σ的字母表Σ,称为精确字符串匹配问题。目前,模式匹配是在生物序列数据库中定位核苷酸或氨基酸序列模式的有力工具。搜索一组模式P0 P1 P2…r-1, r≥1,在给定文本T中称为多模式字符串匹配问题。多模式字符串匹配问题以前已经通过有效的位并行字符串匹配算法:shift-or和BNDM来解决。许多其他类型的算法也存在于相同的目的,但比特并行已被证明比其他算法更有效。在本文中,我们用q-gram (B. Durian et al., 2008)扩展了BNDM算法,用于多模式,其中每个多模式是任意DNA模式。我们假设每个模式的大小为m,模式的总长度小于或等于所用计算机的字长(w)。由于BNDM算法已被证明比其他任何位并行字符串匹配算法都要快(G. Navarro, 2000),因此,我们比较了多模式q-gram BNDM算法与现有BNDM算法在不同q值和模式数(r)下的性能。
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A fast bit-parallel multi-patterns string matching algorithm for biological sequences
The problem of searching occurrences of a pattern P[0...m-1] in the text T[0...n-1>with m ≤ n, where the symbols of P and T are drawn from some alphabet Σ of size σ, is called exact string matching problem. In the present day, pattern matching is a powerful tool in locating nucleotide or amino acid sequence patterns in the biological sequence database. The problem of searching a set of patterns P0, P1, P2...Pr-1, r ≥ 1, in the given text T is called multi-pattern string matching problem. The multi-patterns string matching problem has been previously solved by efficient bit-parallel strings matching algorithms: shift-or and BNDM. Many other types of algorithms also exist for the same purpose, but bit-parallelism has been shown to be very efficient than the others. In this paper, we extend BNDM algorithm with q-gram (B. Durian et al., 2008) for multiple patterns, where each multi-patterns are any DNA patterns. We assume that each pattern is of equal size m and total length of pattern is less than or equal to word length (w) of computer used. Since BNDM algorithm has been shown to be faster than any other bit-parallel string matching algorithm (G. Navarro, 2000), therefore, we compare the performance of multi-patterns q-gram BNDM algorithm with existing BNDM algorithm for different value of q and number of patterns (r).
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来源期刊
In Silico Biology
In Silico Biology Computer Science-Computational Theory and Mathematics
CiteScore
2.20
自引率
0.00%
发文量
1
期刊介绍: The considerable "algorithmic complexity" of biological systems requires a huge amount of detailed information for their complete description. Although far from being complete, the overwhelming quantity of small pieces of information gathered for all kind of biological systems at the molecular and cellular level requires computational tools to be adequately stored and interpreted. Interpretation of data means to abstract them as much as allowed to provide a systematic, an integrative view of biology. Most of the presently available scientific journals focus either on accumulating more data from elaborate experimental approaches, or on presenting new algorithms for the interpretation of these data. Both approaches are meritorious.
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