网络药理学的应用研究与发展

军军 张
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引用次数: 2

摘要

网络药理学是一门以系统生物学原理为基础,解释疾病发展过程,并进一步利用网络平衡的整体观点来理解药物与生物体之间相互作用的学科。它以“多基因、多靶点”的特点,开创了多靶点与多种疾病之间复杂网络关系的新模式,在复杂疾病的发病机制和治疗靶点研究中具有重要的应用价值。本文对网络药理学的相关技术以及网络药理学在药物与中药结合中的应用进行综述,为药理学的进一步研究开辟新的思路。
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Application Research and Development of Network Pharmacology
Cyberpharmacology is a discipline that explains the process of disease development based on the principles of systems biology, and further uses the holistic view of network balance to understand the interaction between drugs and organisms. With the characteristics of “multi-gene, multi-target”, it has created a new pattern of complex network relationship between multi-target and multiple diseases, which has important application value in the research of pathogenesis and therapeutic targets of complex diseases. In this paper, the related technology of network pharmacology and the application of network pharmacology in combination drugs and traditional Chinese medicine are reviewed, which will open up new ideas for the further study on pharmacology.
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