{"title":"血管生成素调控细胞凋亡的机制及作用。","authors":"L. Shu-ping, H. Guo-fu","doi":"10.13865/J.CNKI.CJBMB.2015.12.05","DOIUrl":null,"url":null,"abstract":"Angiogenin (ANG), a secreted ribonuclease, has been characterized recently as an anti-apoptosis factor involved in a variety of cellular anti-apoptosis process. ANG regulates intrinsic pathways-related major molecules such as anti-apoptotic protein Bcl-2, as well as extrinsic signaling pathways. Moreover, ANG regulates p53-regulated apoptosis, a process considered to be important in regulating both the extrinsic and the intrinsic pathways.","PeriodicalId":9907,"journal":{"name":"中国生物化学与分子生物学报","volume":"31 12 1","pages":"1258-1260"},"PeriodicalIF":0.0000,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":"{\"title\":\"Mechanism and Function of Angiogenin in Apoptosis Regulation.\",\"authors\":\"L. Shu-ping, H. Guo-fu\",\"doi\":\"10.13865/J.CNKI.CJBMB.2015.12.05\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Angiogenin (ANG), a secreted ribonuclease, has been characterized recently as an anti-apoptosis factor involved in a variety of cellular anti-apoptosis process. ANG regulates intrinsic pathways-related major molecules such as anti-apoptotic protein Bcl-2, as well as extrinsic signaling pathways. Moreover, ANG regulates p53-regulated apoptosis, a process considered to be important in regulating both the extrinsic and the intrinsic pathways.\",\"PeriodicalId\":9907,\"journal\":{\"name\":\"中国生物化学与分子生物学报\",\"volume\":\"31 12 1\",\"pages\":\"1258-1260\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中国生物化学与分子生物学报\",\"FirstCategoryId\":\"1089\",\"ListUrlMain\":\"https://doi.org/10.13865/J.CNKI.CJBMB.2015.12.05\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国生物化学与分子生物学报","FirstCategoryId":"1089","ListUrlMain":"https://doi.org/10.13865/J.CNKI.CJBMB.2015.12.05","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Mechanism and Function of Angiogenin in Apoptosis Regulation.
Angiogenin (ANG), a secreted ribonuclease, has been characterized recently as an anti-apoptosis factor involved in a variety of cellular anti-apoptosis process. ANG regulates intrinsic pathways-related major molecules such as anti-apoptotic protein Bcl-2, as well as extrinsic signaling pathways. Moreover, ANG regulates p53-regulated apoptosis, a process considered to be important in regulating both the extrinsic and the intrinsic pathways.
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