更正:与Gelofusine相比,白蛋白在严重疟疾儿童中的体积扩张:一项对照试验的结果

S. Akech, Samson Gwer, R. Idro, G. Fegan, A. C. Eziefula, C. Newton, M. Levin, K. Maitland
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引用次数: 4

摘要

试验结果:研究人员发现,在主要结局(开始补液后8小时血液中休克和酸中毒的纠正)或死亡率方面,给予Gelofusine和给予白蛋白的儿童没有显著差异。然后,研究人员将该试验的死亡率数据与另外两项白蛋白组试验的数据结合起来。这一综合分析表明,白蛋白的死亡率低于其他液体,无论是Gelofusine还是盐溶液。
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Correction: Volume Expansion with Albumin Compared to Gelofusine in Children with Severe Malaria: Results of a Controlled Trial
What this trial shows: The investigators found no significant differences in the primary outcomes (correction of shock and acidosis in the blood 8 h after fluids were started) or in death rates between children given Gelofusine and those given albumin. The researchers then combined the data on death rates from this trial with data from two other trials with an albumin arm. This combined analysis suggested that death rates with albumin were lower than with other fluids, either Gelofusine or salt solution.
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